ID   3.1.1.64
DE   retinoid isomerohydrolase.
AN   all-trans-retinylester 11-cis isomerohydrolase.
AN   all-trans-retinyl-palmitate hydrolase.
CA   an all-trans-retinyl ester + H2O = 11-cis-retinol + a fatty acid + H(+).
CC   -!- This enzyme, which operates in the retinal pigment epithelium (RPE),
CC       catalyzes the cleavage and isomerization of all-trans-retinyl fatty
CC       acid esters to 11-cis-retinol, a key step in the regeneration of the
CC       visual chromophore in the vertebrate visual cycle.
CC   -!- Interaction of the enzyme with the membrane is critical for its
CC       enzymatic activity.
CC   -!- Formerly EC 5.2.1.7.
DR   Q6PBW5, RP65A_DANRE;  A9C3R8, RP65C_DANRE;  Q9YI25, RPE65_AMBTI;
DR   Q28175, RPE65_BOVIN;  Q9TVB8, RPE65_CANLF;  Q9YGX2, RPE65_CHICK;
DR   Q9XT71, RPE65_CHLAE;  Q8AXN9, RPE65_CYNPY;  Q16518, RPE65_HUMAN;
DR   Q91ZQ5, RPE65_MOUSE;  O70276, RPE65_RAT  ;
//