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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.1.1.78

Accepted Name
Polyneuridine-aldehyde esterase.
Alternative Name(s)
PNAE.
Polyneuridine aldehyde esterase.
Reaction catalysed
Polyneuridine aldehyde + H(2)O <=> 16-epivellosimine + CO(2) + methanol
Comment(s)
  • Following hydrolysis of this indole alkaloid ester, the carboxylic acid decarboxylates spontaneously giving the sarpagan skeleton.
  • Also acts on akuammidine aldehyde (the 16-epimer of polyneuridine aldehyde).
Cross-references
BRENDA3.1.1.78
EC2PDB3.1.1.78
ExplorEnz3.1.1.78
PRIAM enzyme-specific profiles3.1.1.78
KEGG Ligand Database for Enzyme Nomenclature3.1.1.78
IUBMB Enzyme Nomenclature3.1.1.78
IntEnz3.1.1.78
MEDLINEFind literature relating to 3.1.1.78
MetaCyc3.1.1.78
UniProtKB/Swiss-Prot
Q9SE93, PNAE_RAUSE

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-