ENZYME entry: EC 3.1.1.93
| Accepted Name | ||||||
|---|---|---|---|---|---|---|
| mycophenolic acid acyl-glucuronide esterase | ||||||
| Alternative Name(s) | ||||||
| AcMPAG deglucuronidase | ||||||
| mycophenolic acid acyl-glucuronide deglucuronidase | ||||||
| Reaction catalysed | ||||||
| H2O + mycophenolic acid O-acyl-beta-D-glucuronide = D-glucuronate + H(+) + mycophenolate | ||||||
| Comment(s) | ||||||
| This liver enzyme deglucuronidates mycophenolic acid O-acyl- glucuronide, a metabolite of the immunosuppressant drug mycophenolate that is thought to be immunotoxic. | ||||||
| Cross-references | ||||||
| BRENDA | 3.1.1.93 | |||||
| EC2PDB | 3.1.1.93 | |||||
| ExplorEnz | 3.1.1.93 | |||||
| PRIAM enzyme-specific profiles | 3.1.1.93 | |||||
| KEGG Ligand Database for Enzyme Nomenclature | 3.1.1.93 | |||||
| IUBMB Enzyme Nomenclature | 3.1.1.93 | |||||
| IntEnz | 3.1.1.93 | |||||
| MEDLINE | Find literature relating to 3.1.1.93 | |||||
| MetaCyc | 3.1.1.93 | |||||
| Rhea expert-curated reactions | 3.1.1.93 | |||||
| UniProtKB/Swiss-Prot |
| |||||
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