ENZYME entry: EC 3.1.1.93
Accepted Name |
Mycophenolic acid acyl-glucuronide esterase.
|
Alternative Name(s) |
AcMPAG deglucuronidase. |
Mycophenolic acid acyl-glucuronide deglucuronidase. |
Reaction catalysed |
Mycophenolic acid O-acyl-glucuronide + H(2)O <=> mycophenolate + D-glucuronate |
Comment(s) |
This liver enzyme deglucuronidates mycophenolic acid O-acyl-
glucuronide, a metabolite of the immunosuppressant drug mycophenolate
that is thought to be immunotoxic.
|
Cross-references |
BRENDA | 3.1.1.93 |
EC2PDB | 3.1.1.93 |
ExplorEnz | 3.1.1.93 |
PRIAM enzyme-specific profiles | 3.1.1.93 |
KEGG Ligand Database for Enzyme Nomenclature | 3.1.1.93 |
IUBMB Enzyme Nomenclature | 3.1.1.93 |
IntEnz | 3.1.1.93 |
MEDLINE | Find literature relating to 3.1.1.93 |
MetaCyc | 3.1.1.93 |
Rhea expert-curated reactions | 3.1.1.93 |
UniProtKB/Swiss-Prot |
|
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