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ENZYME

ENZYME entry: EC 3.1.1.96

Accepted Name
D-aminoacyl-tRNA deacylase
Alternative Name(s)
D-tyrosyl-tRNA(Tyr) aminoacylhydrolase
D-Tyr-tRNA(Tyr) deacylase
Reaction catalysed
  • a D-aminoacyl-tRNA + H2O <=> a D-alpha-amino acid + a tRNA + H(+)
  • glycyl-tRNA(Ala) + H2O <=> glycine + H(+) + tRNA(Ala)
Comment(s)
  • The enzyme, found in all domains of life, can cleave mischarged glycyl-tRNA(Ala).
  • The enzyme from Escherichia coli can cleave D-tyrosyl-tRNA(Tyr), D-aspartyl-tRNA(Asp) and D-tryptophanyl-tRNA(Trp).
  • Whereas the enzyme from the archaeon Pyrococcus abyssi is a zinc protein, the enzyme from Escherichia coli does not carry any zinc.
  • Formerly EC 3.6.1.n1.
Cross-references
BRENDA3.1.1.96
EC2PDB3.1.1.96
ExplorEnz3.1.1.96
PRIAM enzyme-specific profiles3.1.1.96
KEGG Ligand Database for Enzyme Nomenclature3.1.1.96
IUBMB Enzyme Nomenclature3.1.1.96
IntEnz3.1.1.96
MEDLINEFind literature relating to 3.1.1.96
MetaCyc3.1.1.96
Rhea expert-curated reactions3.1.1.96
UniProtKB/Swiss-Prot
Q2T9V8, DTD1_BOVINF1QGC8, DTD1_DANREQ8TEA8, DTD1_HUMAN
Q4Q1E7, DTD1_LEIMAQ9DD18, DTD1_MOUSEE1C762, DTD2_CHICK
Q68EL2, DTD2_DANREQ96FN9, DTD2_HUMANQ8BHA3, DTD2_MOUSE
P73335, DTD3_SYNY3Q9YBW7, DTDA_AERPEO29630, DTDA_ARCFU
A8MCV2, DTDA_CALMQA0RUG0, DTDA_CENSYB8D4Z8, DTDA_DESA1
B9LV23, DTDA_HALLTQ5V452, DTDA_HALMAB0R384, DTDA_HALS3
Q9HS70, DTDA_HALSAQ18KS1, DTDA_HALWDA2BKX3, DTDA_HYPBU
A8ABM7, DTDA_IGNH4B1L7I3, DTDA_KORCOA6UUZ4, DTDA_META3
P58850, DTDA_METACA7IAL9, DTDA_METB6Q46AI3, DTDA_METBF
Q12UQ4, DTDA_METBUQ2FPX3, DTDA_METHJQ57630, DTDA_METJA
P58851, DTDA_METKAA2STU3, DTDA_METLZA4FY35, DTDA_METM5
A6VFS5, DTDA_METM7Q8PS92, DTDA_METMAA3CSJ1, DTDA_METMJ
Q6LYK1, DTDA_METMPB8GIX8, DTDA_METPEA4YEU7, DTDA_METS5
A0B5C3, DTDA_METTPA6UP03, DTDA_METVSQ3ITN8, DTDA_NATPD
Q6L1F5, DTDA_PICTOQ9V2R8, DTDA_PYRABQ8ZVE0, DTDA_PYRAE
A4WL31, DTDA_PYRARA3MWS2, DTDA_PYRCJP58852, DTDA_PYRFU
O57774, DTDA_PYRHOA1RS86, DTDA_PYRILB1Y9H2, DTDA_PYRNV
Q97WI2, DTDA_SACS2A3DLP6, DTDA_STAMFQ4JCK7, DTDA_SULAC
C3N0C0, DTDA_SULIAC4KJG8, DTDA_SULIKC3MJC8, DTDA_SULIL
C3MTR0, DTDA_SULIMC3NJ84, DTDA_SULINC3N7X8, DTDA_SULIY
Q96YQ2, DTDA_SULTOQ9HM47, DTDA_THEACC5A422, DTDA_THEGJ
Q5JH30, DTDA_THEKOB6YSX3, DTDA_THEONQ97CM5, DTDA_THEVO
B0BZ98, DTD_ACAM1A3DF46, DTD_ACET2Q6F6W0, DTD_ACIAD
B7GUW9, DTD_ACIB3B7I245, DTD_ACIB5B2I1P4, DTD_ACIBC
B0VP57, DTD_ACIBSA3MA28, DTD_ACIBTB0V9V8, DTD_ACIBY
A0LQX9, DTD_ACIC1B9MCH0, DTD_ACIETA1WC42, DTD_ACISJ
A3N3P1, DTD_ACTP2B3H319, DTD_ACTP7B0BTX7, DTD_ACTPJ
A6VL72, DTD_ACTSZA0KEZ2, DTD_AERHHB2UQS5, DTD_AKKM8
Q220S3, DTD_ALBFTQ0VM94, DTD_ALCBSQ5E8Q0, DTD_ALIF1
B5FFD2, DTD_ALIFMB6EGQ6, DTD_ALISLQ5WHP9, DTD_ALKCK
Q0A5C9, DTD_ALKEHA6TQP0, DTD_ALKMQA8MGN0, DTD_ALKOO
B4RYB0, DTD_ALTMDQ2IMC5, DTD_ANADEB7GFP2, DTD_ANOFW
O66742, DTD_AQUAEQ5P951, DTD_AROAEB6YS15, DTD_AZOPC
A1K1M2, DTD_AZOSBC1DHT6, DTD_AZOVDC3P993, DTD_BACAA
C3L611, DTD_BACACA0RJ14, DTD_BACAHA0A023W421, DTD_BACAM
Q81LI3, DTD_BACANB7JPZ2, DTD_BACC0Q730C6, DTD_BACC1
B7IIR8, DTD_BACC2C1ESV0, DTD_BACC3B7HE40, DTD_BACC4
B7HQG5, DTD_BACC7A7GT88, DTD_BACCNB9IYY0, DTD_BACCQ
Q817X5, DTD_BACCRQ634D8, DTD_BACCZQ5LIY8, DTD_BACFN
Q650H8, DTD_BACFRQ6HDC0, DTD_BACHKQ65GR0, DTD_BACLD
A9VIN2, DTD_BACMKA8FFP8, DTD_BACP2Q8A2P0, DTD_BACTN
A7Z754, DTD_BACVZQ6MMK8, DTD_BDEBAC5C226, DTD_BEUC1
B8DSS1, DTD_BIFA0A1A216, DTD_BIFAAB3DQN7, DTD_BIFLD
Q8G4Q2, DTD_BIFLOB7GQ87, DTD_BIFLSC0ZAQ1, DTD_BREBN
B1YTD6, DTD_BURA4A0K4L0, DTD_BURCHB4EET1, DTD_BURCJ
Q0BI86, DTD_BURCMQ39JJ5, DTD_BURL3A9AH76, DTD_BURM1
A3MP68, DTD_BURM7A2S590, DTD_BURM9Q62HB3, DTD_BURMA
A1V060, DTD_BURMSB1JVU9, DTD_BURO0Q1BZ40, DTD_BURO1
Q3JNS1, DTD_BURP1Q63QX1, DTD_BURPSQ2SZ60, DTD_BURTA
A4JBK9, DTD_BURVGB9ML29, DTD_CALBDQ8RAL7, DTD_CALS4
A4XI81, DTD_CALS8Q6FT39, DTD_CANGAQ3A9Z9, DTD_CARHZ
B3PHR3, DTD_CELJUA3PI75, DTD_CERS1Q3J474, DTD_CERS4
B9KPE1, DTD_CERSKA9WE39, DTD_CHLAAB8G857, DTD_CHLAD
B3EG59, DTD_CHLL2B3QL07, DTD_CHLP8A1BI65, DTD_CHLPD
B9LIV8, DTD_CHLSYB3QTV8, DTD_CHLT3Q8KBF6, DTD_CHLTE
A0LY87, DTD_CHRFKQ1QSS9, DTD_CHRSDQ7NYM3, DTD_CHRVO
B5EAS6, DTD_CITBBA8AL53, DTD_CITK8Q97GU2, DTD_CLOAB
A7FY07, DTD_CLOB1C3KTC0, DTD_CLOB6A6LTN7, DTD_CLOB8
B2V347, DTD_CLOBAB2TN01, DTD_CLOBBA5I6D9, DTD_CLOBH
C1FKE9, DTD_CLOBJB1IME1, DTD_CLOBKA7GHS6, DTD_CLOBL
B1L0A0, DTD_CLOBMQ183H9, DTD_CLOD6A5N1Z2, DTD_CLOK5
A0PZW6, DTD_CLONNQ0TP24, DTD_CLOP1Q8XJ24, DTD_CLOPE
Q0SRP4, DTD_CLOPSQ892A9, DTD_CLOTEQ489A4, DTD_COLP3
Q8FPG8, DTD_COREFA4QES6, DTD_CORGBQ8NP96, DTD_CORGL
C4LJ12, DTD_CORK4B1VDF7, DTD_CORU7A7MQD6, DTD_CROS8
Q1LRC2, DTD_CUPMCQ0KED0, DTD_CUPNHQ475S4, DTD_CUPPJ
B2AH66, DTD_CUPTRQ6AAW5, DTD_CUTAKB8HUW5, DTD_CYAP4
Q11RA1, DTD_CYTH3Q47K67, DTD_DECARQ3ZAH5, DTD_DEHM1
A5FSN9, DTD_DEHMBQ3ZWA4, DTD_DEHMCC1CUI9, DTD_DEIDV
Q1IY72, DTD_DEIGDQ9RVY1, DTD_DEIRAA9BUE9, DTD_DELAS
B8FHU4, DTD_DESALB1I337, DTD_DESAPB8J080, DTD_DESDA
B8FQT8, DTD_DESHDQ24UQ3, DTD_DESHYA8ZUJ9, DTD_DESOH
Q6AS26, DTD_DESPSA4J2H0, DTD_DESRMQ72C32, DTD_DESVH
A1VDX8, DTD_DESVVQ54EY1, DTD_DICDIA5EVP7, DTD_DICNV
B5YDT2, DTD_DICT6B8E1C2, DTD_DICTDA8LJ36, DTD_DINSH
Q9VGP0, DTD_DROMEA7ZU92, DTD_ECO24B7UNK4, DTD_ECO27
B7MI18, DTD_ECO45B7L9D6, DTD_ECO55P0A6M6, DTD_ECO57
B5YZ24, DTD_ECO5EB7NUY4, DTD_ECO7IB7N2M8, DTD_ECO81
B7M686, DTD_ECO8AC5A055, DTD_ECOBWB1XB55, DTD_ECODH
A8A6Y8, DTD_ECOHSA1AI64, DTD_ECOK1Q0TAH5, DTD_ECOL5
P0A6M5, DTD_ECOL6B1IVJ1, DTD_ECOLCP0A6M4, DTD_ECOLI
B7NFI6, DTD_ECOLUB6I4M4, DTD_ECOSEB1LMS1, DTD_ECOSM
Q1R431, DTD_ECOUTC5BC71, DTD_EDWI9A4WGB6, DTD_ENT38
Q833H9, DTD_ENTFAQ75E22, DTD_EREGSB2VFA6, DTD_ERWT9
B7LVG2, DTD_ESCF3B1YJF9, DTD_EXIS2C4L533, DTD_EXISA
A7HLZ9, DTD_FERNBB0S1I7, DTD_FINM2A5FMN0, DTD_FLAJ1
A6GW89, DTD_FLAPJB0TW90, DTD_FRAP2A7N982, DTD_FRATF
Q2A5Z4, DTD_FRATHA0Q402, DTD_FRATNQ0BP79, DTD_FRATO
A4J0B0, DTD_FRATWQ8RGF0, DTD_FUSNNB9M4M9, DTD_GEODF
Q5KWS4, DTD_GEOKAQ39RA1, DTD_GEOMGQ74FT1, DTD_GEOSL
C6DYE1, DTD_GEOSMC5D512, DTD_GEOSWA4IR99, DTD_GEOTN
A5GC79, DTD_GEOURB8F6K3, DTD_GLAP5B7KKT8, DTD_GLOC7
Q7VN41, DTD_HAEDUQ4QMP6, DTD_HAEI8A5UE61, DTD_HAEIE
A5UHF9, DTD_HAEIGP44814, DTD_HAEINQ2SN53, DTD_HAHCH
Q9KDH0, DTD_HALH5A1WW09, DTD_HALHLB8CXE9, DTD_HALOH
B0TF85, DTD_HELMIA9B6D5, DTD_HERA2A4G1U1, DTD_HERAR
Q0I2T9, DTD_HISS1B0UTI6, DTD_HISS2Q31JB0, DTD_HYDCU
Q5QV32, DTD_IDILOA6SUP6, DTD_JANMAQ28NX0, DTD_JANSC
A6W6D7, DTD_KINRDB5XZI4, DTD_KLEP3A6TG77, DTD_KLEP7
Q6CRI9, DTD_KLULAB2GIA9, DTD_KOCRDQ1IHZ8, DTD_KORVE
C5CGW6, DTD_KOSOTQ5FKI6, DTD_LACACB3WEN3, DTD_LACCB
Q1GAH0, DTD_LACDAQ04AV5, DTD_LACDBC4Z1C2, DTD_LACE2
Q043X5, DTD_LACGAA8YUZ8, DTD_LACH4Q74IX3, DTD_LACJO
Q9CJ92, DTD_LACLAA2RHI6, DTD_LACLMQ033A2, DTD_LACLS
Q038Q9, DTD_LACP3A9KK74, DTD_LACP7Q88VQ3, DTD_LACPL
C1DAD5, DTD_LARHHQ38XN8, DTD_LATSSQ5X472, DTD_LEGPA
A5ID02, DTD_LEGPCQ5ZUF4, DTD_LEGPHQ5WVK6, DTD_LEGPL
B1MZI4, DTD_LEUCKQ03WG3, DTD_LEUMMQ03SF0, DTD_LEVBA
Q1WTX9, DTD_LIGS1B2GBW6, DTD_LIMF3A5VJG2, DTD_LIMRD
B2G6X7, DTD_LIMRJQ92BJ1, DTD_LISINC1KVG9, DTD_LISMC
Q71ZE8, DTD_LISMFB8DHM6, DTD_LISMHQ93RD9, DTD_LISMO
A0AIX1, DTD_LISW6B1HV77, DTD_LYSSCB9E709, DTD_MACCJ
A0L7S8, DTD_MAGMMQ65WM2, DTD_MANSMA6VT94, DTD_MARMS
A1TYQ0, DTD_MARN8C6BS14, DTD_MARSDQ607L6, DTD_METCA
B3DVT5, DTD_METI4A2SKK9, DTD_METPPQ2NG79, DTD_METST
C5CCH1, DTD_MICLCQ2RHV8, DTD_MOOTAA0QGF1, DTD_MYCA1
B1MIM7, DTD_MYCA9P63996, DTD_MYCBOA1KJW2, DTD_MYCBP
C1APH7, DTD_MYCBTA4T8S3, DTD_MYCGIB2HD97, DTD_MYCMM
Q73ZI0, DTD_MYCPAA0R080, DTD_MYCS2A5U3R6, DTD_MYCTA
P9WNS8, DTD_MYCTOP9WNS9, DTD_MYCTUA0PSA3, DTD_MYCUA
A1TDH1, DTD_MYCVPQ1DDE5, DTD_MYXXDB2A2F7, DTD_NATTJ
B9L8Z4, DTD_NAUPAQ5F6A6, DTD_NEIG1B4RNL5, DTD_NEIG2
Q9JST7, DTD_NEIMAQ9K143, DTD_NEIMBA1KVT7, DTD_NEIMF
Q3JD71, DTD_NITOCA6Q128, DTD_NITSBQ5Z1P0, DTD_NOCFA
Q8EPR6, DTD_OCEIHQ04HP9, DTD_OENOBB1ZZ94, DTD_OPITP
A1TUZ5, DTD_PARC0A6LG62, DTD_PARD8A1B2U5, DTD_PARDP
B2JGU7, DTD_PARP8B2SYK5, DTD_PARPJQ6MEB9, DTD_PARUW
Q13UB7, DTD_PARXLQ9CKK0, DTD_PASMUQ6DB68, DTD_PECAS
C6DJD2, DTD_PECCPQ03F48, DTD_PEDPAA1ALA7, DTD_PELPD
A5D3E0, DTD_PELTSC0QT00, DTD_PERMHA9BIE9, DTD_PETMO
Q7N9S2, DTD_PHOLLQ6LLR9, DTD_PHOPRA6KZN7, DTD_PHOV8
Q8IIS0, DTD_PLAF7A1VJK0, DTD_POLNAQ124Q1, DTD_POLSJ
B2RM63, DTD_PORG3Q7MTG7, DTD_PORGIB4S4I3, DTD_PROA2
B4EZB4, DTD_PROMHQ48PK8, DTD_PSE14Q15NT8, DTD_PSEA6
A6VDK2, DTD_PSEA7B7V3H2, DTD_PSEA8Q02ET8, DTD_PSEAB
Q9HUA4, DTD_PSEAEQ1I3R4, DTD_PSEE4Q4KJM7, DTD_PSEF5
C3K814, DTD_PSEFSA4XPL8, DTD_PSEMYA5WA61, DTD_PSEP1
Q3KJE0, DTD_PSEPFB0KM52, DTD_PSEPGQ88D02, DTD_PSEPK
B1J2R2, DTD_PSEPWQ87UX9, DTD_PSESMQ3IJ42, DTD_PSET1
Q4ZZH6, DTD_PSEU2Q4FQD6, DTD_PSYA2Q1Q8K9, DTD_PSYCK
A1T099, DTD_PSYINA5WH93, DTD_PSYWFQ8Y239, DTD_RALN1
Q7UFW2, DTD_RHOBAQ0S3F3, DTD_RHOJRC1B035, DTD_RHOOB
B7K3F6, DTD_RIPO1A7NLC3, DTD_ROSCSQ168K5, DTD_ROSDO
A5UW19, DTD_ROSS1Q1ATQ8, DTD_RUBXDQ5LP58, DTD_RUEPO
Q1GFL4, DTD_RUESTB8I3F5, DTD_RUMCHQ21NB9, DTD_SACD2
B5F000, DTD_SALA4A9MIA3, DTD_SALARQ57HI8, DTD_SALCH
B5FP17, DTD_SALDCB5QWW2, DTD_SALEPB5RFE5, DTD_SALG2
B4TBW0, DTD_SALHSB4SZX0, DTD_SALNSQ5PKE2, DTD_SALPA
A9MZA2, DTD_SALPBC0Q3J4, DTD_SALPCB5BJ27, DTD_SALPK
Q2S3D4, DTD_SALRDB4TPN8, DTD_SALSVP58532, DTD_SALTI
P58533, DTD_SALTYO14274, DTD_SCHPOA8GLH9, DTD_SERP5
A1SB48, DTD_SHEAMB8E4B8, DTD_SHEB2A3CZD8, DTD_SHEB5
A6WI48, DTD_SHEB8A9KXA7, DTD_SHEB9Q12IK4, DTD_SHEDO
Q088X0, DTD_SHEFNB0TPR8, DTD_SHEHHA3QIW0, DTD_SHELP
Q8E988, DTD_SHEONA8H9H9, DTD_SHEPAA4Y2G8, DTD_SHEPC
B8CHJ7, DTD_SHEPWA0KRY8, DTD_SHESAA8FPZ5, DTD_SHESH
Q0HNG8, DTD_SHESMQ0HQC0, DTD_SHESRA1REM9, DTD_SHESW
B1KLY5, DTD_SHEWMB2TVN1, DTD_SHIB3Q31UA6, DTD_SHIBS
Q32A57, DTD_SHIDSQ0SZ73, DTD_SHIF8P0A6M7, DTD_SHIFL
Q3YV89, DTD_SHISSQ2NQS5, DTD_SODGMC4XMR7, DTD_SOLM1
Q01RT2, DTD_SOLUEA9GKM6, DTD_SORC5A7X347, DTD_STAA1
A6U2A1, DTD_STAA2Q2FG94, DTD_STAA3Q2FXU2, DTD_STAA8
A5ITF7, DTD_STAA9Q2YT97, DTD_STAABQ5HFD0, DTD_STAAC
A6QHH5, DTD_STAAEP0A025, DTD_STAAMP0A026, DTD_STAAN
Q6GG71, DTD_STAARQ6G8T6, DTD_STAASA8Z2G0, DTD_STAAT
P0A028, DTD_STAAUP0A027, DTD_STAAWB9DNG1, DTD_STACT
Q5HNR9, DTD_STAEQQ8CP01, DTD_STAESQ4L6X8, DTD_STAHJ
Q49Y71, DTD_STAS1Q3JZ09, DTD_STRA1P63997, DTD_STRA3
P63998, DTD_STRA5Q82G71, DTD_STRAWQ9K4F6, DTD_STRCO
C0M9F6, DTD_STRE4B4U592, DTD_STREMQ54088, DTD_STREQ
A8AZ80, DTD_STRGCB1VS48, DTD_STRGGQ54235, DTD_STRGR
B4SKG5, DTD_STRM5B2FIQ2, DTD_STRMKQ8DS08, DTD_STRMU
P63999, DTD_STRP1Q04JC5, DTD_STRP2P0DA80, DTD_STRP3
B5E6S0, DTD_STRP4Q5X9T5, DTD_STRP6C1C8N4, DTD_STRP7
P64001, DTD_STRP8Q1JJU8, DTD_STRPCQ1JEU0, DTD_STRPD
Q1J4K7, DTD_STRPFA2RGJ5, DTD_STRPGB1I710, DTD_STRPI
B8ZM41, DTD_STRPJQ48R77, DTD_STRPMQ97PH3, DTD_STRPN
P0DA81, DTD_STRPQB2IRP8, DTD_STRPSB5XIM6, DTD_STRPZ
Q8DNX2, DTD_STRR6A4W4G5, DTD_STRS2C0MF91, DTD_STRS7
A3CKK5, DTD_STRSVA4VY70, DTD_STRSYQ5M1S1, DTD_STRT1
Q5M6B2, DTD_STRT2Q03MP9, DTD_STRTDB9DTB9, DTD_STRU0
C1CFL4, DTD_STRZJC1CLY4, DTD_STRZPC1CSR0, DTD_STRZT
A4VGD5, DTD_STUS1B2V7S8, DTD_SULSYQ67LN1, DTD_SYMTH
Q2LTS7, DTD_SYNASQ3A002, DTD_SYNC1A0LL48, DTD_SYNFM
B1XM75, DTD_SYNP2Q0AYS6, DTD_SYNWWC5BPU7, DTD_TERTT
B7IDL6, DTD_THEABQ9KH11, DTD_THEAQQ47KR7, DTD_THEFY
A6LML3, DTD_THEM4Q9WZI9, DTD_THEMAB9KAP7, DTD_THENN
A5IJ55, DTD_THEP1B0K971, DTD_THEP3B0K0N1, DTD_THEPX
B9L111, DTD_THERPB1L7X6, DTD_THESQQ72K35, DTD_THET2
Q5SJQ9, DTD_THET8B5YJ89, DTD_THEYDB8GU25, DTD_THISH
C4L8J8, DTD_TOLATQ119C3, DTD_TRIEIB3E9B8, DTD_TRIL1
C5CM14, DTD_VARPSB7VHE8, DTD_VIBA3A5F4Q7, DTD_VIBC3
Q9KNJ7, DTD_VIBCHC3LSG8, DTD_VIBCMQ87TE4, DTD_VIBPA
Q8DDS3, DTD_VIBVUQ7MQ06, DTD_VIBVYQ8PG32, DTD_XANAC
Q3BNL9, DTD_XANC5Q4UQ26, DTD_XANC8Q8P4H1, DTD_XANCP
Q2P814, DTD_XANOMQ5H5B9, DTD_XANORQ6C7S6, DTD_YARLI
Q07648, DTD_YEASTA1JHU4, DTD_YERE8A7FCQ4, DTD_YERP3
Q1C247, DTD_YERPAB2JYL4, DTD_YERPBP58534, DTD_YERPE
A9R655, DTD_YERPGQ1CN42, DTD_YERPNA4TSF7, DTD_YERPP
Q66GF4, DTD_YERPSB1JR03, DTD_YERPYQ9ZPQ3, GEK1_ARATH

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
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