ENZYME entry: EC 3.1.11.1

Accepted Name
Exodeoxyribonuclease I.
Alternative Name(s)
E.coli exonuclease I.
Exonuclease I.
Reaction catalysed
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
Comment(s)
  • Preference for single-stranded DNA.
  • The Escherichia coli enzyme hydrolyzes glucosylated DNA.
  • Similar enzymes; mammalian DNase III, exonuclease IV, T2- and T4-induced exodeoxyribonucleases.
  • Formerly EC 3.1.4.25.
Cross-references
BRENDA3.1.11.1
EC2PDB3.1.11.1
ExplorEnz3.1.11.1
PRIAM enzyme-specific profiles3.1.11.1
KEGG Ligand Database for Enzyme Nomenclature3.1.11.1
IUBMB Enzyme Nomenclature3.1.11.1
IntEnz3.1.11.1
MEDLINEFind literature relating to 3.1.11.1
MetaCyc3.1.11.1
UniProtKB/Swiss-Prot
O28552, DP2L_ARCFU;  A0RYM0, DP2L_CENSY;  Q5UZ40, DP2L_HALMA;  
Q9HMX8, DP2L_HALSA;  Q18ER3, DP2L_HALWD;  Q8THG5, DP2L_METAC;  
Q0W5U6, DP2L_METAR;  Q46E19, DP2L_METBF;  Q12TF2, DP2L_METBU;  
Q2FSF9, DP2L_METHJ;  Q59024, DP2L_METJA;  Q8TUV3, DP2L_METKA;  
A2SU54, DP2L_METLZ;  A4G0G9, DP2L_METM5;  A9A8R5, DP2L_METM6;  
A6VI14, DP2L_METM7;  Q8PXH2, DP2L_METMA;  A3CXE7, DP2L_METMJ;  
Q6M191, DP2L_METMP;  Q2NHG2, DP2L_METST;  O27579, DP2L_METTH;  
A0B8K5, DP2L_METTP;  A6URH2, DP2L_METVS;  Q74N29, DP2L_NANEQ;  
Q3IU54, DP2L_NATPD;  Q6L1K9, DP2L_PICTO;  Q9V2F4, DP2L_PYRAB;  
P81409, DP2L_PYRFU;  O57861, DP2L_PYRHO;  Q9HM33, DP2L_THEAC;  
Q5JET0, DP2L_THEKO;  Q97CR6, DP2L_THEVO;  O28484, DP2S_ARCFU;  
B0R7U1, DP2S_HALS3;  Q9HMR7, DP2S_HALSA;  Q58113, DP2S_METJA;  
O27456, DP2S_METTH;  Q9V2F3, DP2S_PYRAB;  P81412, DP2S_PYRFU;  
O57863, DP2S_PYRHO;  Q9HLK5, DP2S_THEAC;  P26019, DPOLA_DROME;  
P57620, EX1_BUCAI;  Q8K923, EX1_BUCAP;  Q89A43, EX1_BUCBP;  
P04995, EX1_ECOLI;  P45188, EX1_HAEIN;  Q9NVH0, EXD2_HUMAN;  
Q8VEG4, EXD2_MOUSE;  P04536, EXOD_BPT4;  

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