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ENZYME

ENZYME entry: EC 3.1.11.2

PURL: https://purl.expasy.org/enzyme/EC/3.1.11.2
Accepted Name
exodeoxyribonuclease III
Alternative Name(s)
E.coli exonuclease III
exonuclease III
Reaction catalysed
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates
Comment(s)
  • Preference for double-stranded DNA.
  • Has endonucleolytic activity near apurinic sites on DNA.
  • Similar enzyme: Haemophilus influenzae exonuclease.
  • Formerly EC 3.1.4.27.
Cross-references
BRENDA3.1.11.2
EC2PDB3.1.11.2
ExplorEnz3.1.11.2
KEGG Ligand Database for Enzyme Nomenclature3.1.11.2
IUBMB Enzyme Nomenclature3.1.11.2
MEDLINEFind literature relating to 3.1.11.2
MetaCyc3.1.11.2
Rhea expert-curated reactions3.1.11.2
UniProtKB/Swiss-Prot
P23196, APEX1_BOVINA0MTA1, APEX1_DANREA1YES6, APEX1_GORGO
P27695, APEX1_HUMANP28352, APEX1_MOUSEA1YFZ3, APEX1_PANPA
A2T6Y4, APEX1_PANTRA2T7I6, APEX1_PONPYP43138, APEX1_RAT
Q5E9N9, APEX2_BOVINQ9UBZ4, APEX2_HUMANQ68G58, APEX2_MOUSE
Q6DDT4, APEX2_XENLAA0A509ADV9, APEX_PLABAO97240, APEX_PLAF7
P87175, APN2_SCHPOP38207, APN2_YEASTP45951, ARP_ARATH
P09030, EX3_ECOLIP44318, EX3_HAEINP0A1B0, EX3_SALTI
P0A1A9, EX3_SALTYP37454, EXOA_BACSUP0A2X3, EXOA_STRPN
P0A2X4, EXOA_STRR6G5EC44, MRT2_CAEELQ99638, RAD9A_HUMAN
Q4R5X9, RAD9A_MACFAQ9Z0F6, RAD9A_MOUSEP14746, REC1_MYCMD
P27864, RRP1_DROMEQ9BG99, TREX1_BOVINQ9NSU2, TREX1_HUMAN
Q91XB0, TREX1_MOUSEQ9BQ50, TREX2_HUMANQ9R1A9, TREX2_MOUSE
O26314, UREND_METTH

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-