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ENZYME entry: EC 3.1.11.5

Accepted Name
exodeoxyribonuclease V.
Alternative Name(s)
E.coli exonuclease V.
exonuclease V.
Reaction catalysed
Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides
Comment(s)
  • Preference for double-stranded DNA.
  • Possesses DNA-dependent ATPase activity.
  • Acts endonucleolytically on single-stranded circular DNA.
  • Similar enzyme: Haemophilus influenzae ATP-dependent DNase.
Cross-references
BRENDA3.1.11.5
EC2PDB3.1.11.5
ExplorEnz3.1.11.5
PRIAM enzyme-specific profiles3.1.11.5
KEGG Ligand Database for Enzyme Nomenclature3.1.11.5
IUBMB Enzyme Nomenclature3.1.11.5
IntEnz3.1.11.5
MEDLINEFind literature relating to 3.1.11.5
MetaCyc3.1.11.5
Rhea expert-curated reactions3.1.11.5
UniProtKB/Swiss-Prot
O51578, RECB_BORBU;  P57529, RECB_BUCAI;  Q8K9A9, RECB_BUCAP;  
Q89AB3, RECB_BUCBP;  Q9PLT8, RECB_CHLMU;  Q9Z7G7, RECB_CHLPN;  
O84645, RECB_CHLTR;  P08394, RECB_ECOLI;  P45157, RECB_HAEIN;  
A0QS29, RECB_MYCS2;  P9WMQ2, RECB_MYCTO;  P9WMQ3, RECB_MYCTU;  
P57528, RECC_BUCAI;  Q8K9B0, RECC_BUCAP;  Q89AB4, RECC_BUCBP;  
P07648, RECC_ECOLI;  P44945, RECC_HAEIN;  A0QS30, RECC_MYCS2;  
P9WIQ4, RECC_MYCTO;  P9WIQ5, RECC_MYCTU;  P57530, RECD_BUCAI;  
Q8K9A8, RECD_BUCAP;  Q89AB2, RECD_BUCBP;  P04993, RECD_ECOLI;  
P45158, RECD_HAEIN;  A0QS28, RECD_MYCS2;  P9WHJ0, RECD_MYCTO;  
P9WHJ1, RECD_MYCTU;  

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