A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.1.13.5
| Accepted Name |
|---|
| Ribonuclease D.
|
| Alternative Name(s) |
|---|
| RNase D. |
| Reaction catalysed |
|---|
| Exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides |
| Cofactor(s) |
|---|
| Mg(2+) or cobalt cation or Mn(2+).
|
| Comment(s) |
|---|
- Alteration of the 3'-terminal base has no effect on the rate of
hydrolysis whereas modification of the 3'-terminal sugar has a major
effect.
- tRNA terminating with a 3'-phosphate is completely inactive.
- This enzyme can convert a tRNA precursor into a mature tRNA.
|
| Cross-references |
|---|
| BRENDA | 3.1.13.5 |
| EC2PDB | 3.1.13.5 |
| ExplorEnz | 3.1.13.5 |
| PRIAM enzyme-specific profiles | 3.1.13.5 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.1.13.5 |
| IUBMB Enzyme Nomenclature | 3.1.13.5 |
| IntEnz | 3.1.13.5 |
| MEDLINE | Find literature relating to 3.1.13.5 |
| MetaCyc | 3.1.13.5 |
| UniProtKB/Swiss-Prot |
| A5G127, RND_ACICJ; | Q6G329, RND_BARHE; | C9XUE4, RND_CROTZ; |
| Q6AJF4, RND_DESPS; | C6C608, RND_DICP7; | P09155, RND_ECOLI; |
| A9H9B7, RND_GLUDA; | Q0BVP4, RND_GRABC; | P44442, RND_HAEIN; |
| Q28RA7, RND_JANSC; | B8EN54, RND_METSB; | Q1QLI8, RND_NITHX; |
| A7HYE5, RND_PARL1; | A6V8R6, RND_PSEA7; | A1SVE6, RND_PSYIN; |
| A8GFH0, RND_SERP5; | A0KXU5, RND_SHESA; | D4Z694, RND_SPHJU; |
| Q5GZ75, RND_XANOR; | Q5NPM2, RND_ZYMMO; |
|
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