Expasy logo

ENZYME

ENZYME entry: EC 3.1.2.22

Accepted Name
palmitoyl-protein hydrolase
Alternative Name(s)
palmitoyl-protein thioesterase
Reaction catalysed
H2O + S-hexadecanoyl-L-cysteinyl-[protein] <=> H(+) + hexadecanoate + L-cysteinyl-[protein]
Comment(s)
  • Specific for long-chain thioesters of fatty acids.
  • Hydrolyzes fatty acids from S-acylated cysteine residues in proteins, palmitoyl cysteine and palmitoyl-CoA.
Cross-references
BRENDA3.1.2.22
EC2PDB3.1.2.22
ExplorEnz3.1.2.22
PRIAM enzyme-specific profiles3.1.2.22
KEGG Ligand Database for Enzyme Nomenclature3.1.2.22
IUBMB Enzyme Nomenclature3.1.2.22
IntEnz3.1.2.22
MEDLINEFind literature relating to 3.1.2.22
MetaCyc3.1.2.22
Rhea expert-curated reactions3.1.2.22
UniProtKB/Swiss-Prot
Q2HJ19, AB17A_BOVINQ96GS6, AB17A_HUMANQ99JW1, AB17A_MOUSE
Q5XIJ5, AB17A_RATQ5ZJ01, AB17B_CHICKQ5VST6, AB17B_HUMAN
Q7M759, AB17B_MOUSEQ6AY17, AB17B_RATQ6DCC5, AB17B_XENLA
Q6DEY3, AB17B_XENTRA5PKD9, AB17C_BOVINQ5ZJX1, AB17C_CHICK
Q7ZVZ7, AB17C_DANREQ6PCB6, AB17C_HUMANQ8VCV1, AB17C_MOUSE
B5DFK7, AB17C_RATQ6DD70, AB17C_XENLAQ6GL10, AB17C_XENTR
Q5E9H9, ABHDA_BOVINQ9NUJ1, ABHDA_HUMANQ6PE15, ABHDA_MOUSE
Q5REX5, ABHDA_PONABQ5I0K5, ABHDA_RATQ21221, AHO3_CAEEL
Q54T49, APT11_DICDIQ55FK4, APT12_DICDIQ4WCX7, APTH1_ASPFU
Q5AGD1, APTH1_CANALQ6FW75, APTH1_CANGAP0CL95, APTH1_CRYNB
P0CL94, APTH1_CRYNJQ6BSS8, APTH1_DEBHAQ5ASI2, APTH1_EMENI
Q750X7, APTH1_EREGSQ4I8Q4, APTH1_GIBZEQ6CJK6, APTH1_KLULA
Q9HFJ5, APTH1_NEUCRO42881, APTH1_SCHPOQ4PID3, APTH1_USTMA
Q6CGL4, APTH1_YARLIQ12354, APTH1_YEASTQ3MHR0, LYPA1_BOVIN
O75608, LYPA1_HUMANP97823, LYPA1_MOUSEQ5RBR7, LYPA1_PONAB
O77821, LYPA1_RABITP70470, LYPA1_RATO95372, LYPA2_HUMAN
Q9WTL7, LYPA2_MOUSEQ9QYL8, LYPA2_RATQ5VWZ2, LYPL1_HUMAN
Q3UFF7, LYPL1_MOUSEQ5R8C2, LYPL1_PONABO59747, PDF1_SCHPO
P45478, PPT1_BOVINQ20390, PPT1_CAEELQ9W3C7, PPT1_DROME
P50897, PPT1_HUMANQ8HXW6, PPT1_MACFAO88531, PPT1_MOUSE
P45479, PPT1_RATQ54CM0, PPT3_DICDI

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-