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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.1.2.22

Accepted Name
Palmitoyl-protein hydrolase.
Alternative Name(s)
Palmitoyl-protein thioesterase.
Reaction catalysed
Palmitoyl-[protein] + H(2)O <=> palmitate + [protein]
Comment(s)
  • Specific for long-chain thioesters of fatty acids.
  • Hydrolyzes fatty acids from S-acylated cysteine residues in proteins, palmitoyl cysteine and palmitoyl-CoA.
Cross-references
BRENDA3.1.2.22
EC2PDB3.1.2.22
ExplorEnz3.1.2.22
PRIAM enzyme-specific profiles3.1.2.22
KEGG Ligand Database for Enzyme Nomenclature3.1.2.22
IUBMB Enzyme Nomenclature3.1.2.22
IntEnz3.1.2.22
MEDLINEFind literature relating to 3.1.2.22
MetaCyc3.1.2.22
UniProtKB/Swiss-Prot
Q2HJ19, AB17A_BOVIN;  Q96GS6, AB17A_HUMAN;  Q99JW1, AB17A_MOUSE;  
Q5XIJ5, AB17A_RAT;  Q5ZJ01, AB17B_CHICK;  Q5VST6, AB17B_HUMAN;  
Q7M759, AB17B_MOUSE;  Q6AY17, AB17B_RAT;  Q6DCC5, AB17B_XENLA;  
Q6DEY3, AB17B_XENTR;  A5PKD9, AB17C_BOVIN;  Q5ZJX1, AB17C_CHICK;  
Q7ZVZ7, AB17C_DANRE;  Q6PCB6, AB17C_HUMAN;  Q8VCV1, AB17C_MOUSE;  
B5DFK7, AB17C_RAT;  Q6DD70, AB17C_XENLA;  Q6GL10, AB17C_XENTR;  
Q21221, AHO3_CAEEL;  O59747, PDF1_SCHPO;  P45478, PPT1_BOVIN;  
Q20390, PPT1_CAEEL;  Q9W3C7, PPT1_DROME;  P50897, PPT1_HUMAN;  
Q8HXW6, PPT1_MACFA;  O88531, PPT1_MOUSE;  P45479, PPT1_RAT;  
Q54CM0, PPT3_DICDI;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-