ENZYME entry: EC 3.1.2.27
Accepted Name |
Choloyl-CoA hydrolase.
|
Alternative Name(s) |
Chenodeoxycholoyl-coenzyme A thioesterase. |
Choloyl-coenzyme A thioesterase. |
Peroxisomal acyl-CoA thioesterase 2. |
PTE-2. |
Reaction catalysed |
Choloyl-CoA + H(2)O <=> cholate + CoA |
Comment(s) |
- Also acts on chenodeoxycholoyl-CoA and to a lesser extent on short-
and medium- to long-chain acyl-CoA's, and other substrates, including
trihydroxycoprostanoyl-CoA, hydroxymethylglutaryl-CoA and branched
chain acyl-CoA's, all of which are present in peroxisomes.
- The enzyme is strongly inhibited by CoA and may be involved in
controlling CoA levels in the peroxisome.
|
Cross-references |
BRENDA | 3.1.2.27 |
EC2PDB | 3.1.2.27 |
ExplorEnz | 3.1.2.27 |
PRIAM enzyme-specific profiles | 3.1.2.27 |
KEGG Ligand Database for Enzyme Nomenclature | 3.1.2.27 |
IUBMB Enzyme Nomenclature | 3.1.2.27 |
IntEnz | 3.1.2.27 |
MEDLINE | Find literature relating to 3.1.2.27 |
MetaCyc | 3.1.2.27 |
UniProtKB/Swiss-Prot |
|
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