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ENZYME entry: EC 3.1.2.28

Accepted Name
1,4-dihydroxy-2-naphthoyl-CoA hydrolase.
Reaction catalysed
1,4-dihydroxy-2-naphthoyl-CoA + H(2)O <=> 1,4-dihydroxy-2-naphthoate + CoA
Comment(s)
  • This enzyme participates in the synthesis of menaquinones, phylloquinone, as well as several plant pigments.
  • The enzyme from the cyanobacterium Synechocystis sp. PCC 6803 does not accept benzoyl-CoA or phenylacetyl-CoA as substrates.
  • Formerly EC 3.1.2.n1.
Cross-references
BRENDA3.1.2.28
EC2PDB3.1.2.28
ExplorEnz3.1.2.28
PRIAM enzyme-specific profiles3.1.2.28
KEGG Ligand Database for Enzyme Nomenclature3.1.2.28
IUBMB Enzyme Nomenclature3.1.2.28
IntEnz3.1.2.28
MEDLINEFind literature relating to 3.1.2.28
MetaCyc3.1.2.28
UniProtKB/Swiss-Prot
B0CEN8, DNCH_ACAM1;  B1WZN0, DNCH_CROS5;  B7KDA3, DNCH_GLOC7;  
B0JQL4, DNCH_MICAN;  B2IZ83, DNCH_NOSP7;  Q8YU89, DNCH_NOSS1;  
A3PAP1, DNCH_PROM0;  A2C002, DNCH_PROM1;  A8G2H9, DNCH_PROM2;  
A2CDA0, DNCH_PROM3;  A9BD34, DNCH_PROM4;  A2BUF0, DNCH_PROM5;  
Q31D08, DNCH_PROM9;  Q7VE16, DNCH_PROMA;  Q7V4A7, DNCH_PROMM;  
Q7V3A9, DNCH_PROMP;  A2BNW8, DNCH_PROMS;  Q46HJ9, DNCH_PROMT;  
B7JXS8, DNCH_RIPO1;  Q31ME5, DNCH_SYNE7;  B1XL26, DNCH_SYNP2;  
Q5MZI3, DNCH_SYNP6;  A5GP76, DNCH_SYNPW;  Q7U3X6, DNCH_SYNPX;  
A5GWA0, DNCH_SYNR3;  Q0I6T4, DNCH_SYNS3;  Q3AVZ5, DNCH_SYNS9;  
Q3AGW5, DNCH_SYNSC;  Q55777, DNCH_SYNY3;  Q8DLK3, DNCH_THEEB;  
Q10XE8, DNCH_TRIEI;  Q3MG63, DNCH_TRIV2;  P77781, MENI_ECOLI;  

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