ID   3.1.21.8
DE   T4 deoxyribonuclease II.
AN   T4 endonuclease II.
CA   Endonucleolytic nicking and cleavage of cytosine-containing double-
CA   stranded DNA.
CC   -!- This phage T4 enzyme is involved in degradation of host DNA.
CC   -!- The enzyme primarily catalyzes nicking of the bottom strand of double
CC       stranded DNA between the first and second base pair to the right of a
CC       top-strand CCGC motif.
CC   -!- Double-stranded breaks are produced 5- to 10-fold less frequently.
CC   -!- It does not cleave the T4 native DNA, which contains
CC       5-hydroxymethylcytosine instead of cytosine.
DR   P07059, END2_BPT4  ;
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