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ENZYME entry: EC 3.1.22.1

Accepted Name
Deoxyribonuclease II.
Alternative Name(s)
DNase II.
Lysosomal DNase II.
Reaction catalysed
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products
Comment(s)
  • Preference for double-stranded DNA.
  • Similar enzymes: crab testis DNase, snail DNase, salmon testis DNase, liver acid DNase, human acid DNases of gastric mucosa and cervix.
  • Formerly EC 3.1.4.6.
Cross-references
BRENDA3.1.22.1
EC2PDB3.1.22.1
ExplorEnz3.1.22.1
PRIAM enzyme-specific profiles3.1.22.1
KEGG Ligand Database for Enzyme Nomenclature3.1.22.1
IUBMB Enzyme Nomenclature3.1.22.1
IntEnz3.1.22.1
MEDLINEFind literature relating to 3.1.22.1
MetaCyc3.1.22.1
Rhea expert-curated reactions3.1.22.1
UniProtKB/Swiss-Prot
Q75WF2, DNA2_ACAPL;  P56541, DNS2A_BOVIN;  O00115, DNS2A_HUMAN;  
P56542, DNS2A_MOUSE;  O62855, DNS2A_PIG;  Q9QZK8, DNS2A_RAT;  
Q8WZ79, DNS2B_HUMAN;  Q9QY48, DNS2B_MOUSE;  Q9QZK9, DNS2B_RAT;  
Q17778, NUC1_CAEEL;  

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