ID 3.1.3.108 DE nocturnin. AN nocturnin (curled). CA (1) H2O + NADPH = NADH + phosphate. CA (2) H2O + NADP(+) = NAD(+) + phosphate. CC -!- The mammalian mitochondrial enzyme is a rhythmically expressed CC protein that regulates metabolism under the control of circadian CC clock. CC -!- It has a slight preference for NADPH over NADP(+). CC -!- The archaeal enzyme, identified in Methanocaldococcus jannaschii, CC is bifunctional acting as NAD kinase (EC 2.7.1.23) and NADP CC phosphatase with a slight preference for NADP(+) over NADPH. DR Q9UK39, NOCT_HUMAN ; O35710, NOCT_MOUSE ; Q9ET55, NOCT_RAT ; //