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ENZYME entry: EC 3.1.3.57

Accepted Name
Inositol-1,4-bisphosphate 1-phosphatase.
Alternative Name(s)
Inositol polyphosphate 1-phosphatase.
Reaction catalysed
1D-myo-inositol 1,4-bisphosphate + H(2)O <=> 1D-myo-inositol 4-phosphate + phosphate
Comment(s)
  • Acts on inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate (forming inositol 3,4-bisphosphate) with similar V(max) for both substrates, but with a 5 times higher affinity for the bisphosphate.
  • Does not act on inositol 1-phosphate, inositol 1,4,5-trisphosphate or inositol 1,3,4,5-tetrakisphosphate.
Cross-references
PROSITEPDOC00547
BRENDA3.1.3.57
EC2PDB3.1.3.57
ExplorEnz3.1.3.57
PRIAM enzyme-specific profiles3.1.3.57
KEGG Ligand Database for Enzyme Nomenclature3.1.3.57
IUBMB Enzyme Nomenclature3.1.3.57
IntEnz3.1.3.57
MEDLINEFind literature relating to 3.1.3.57
MetaCyc3.1.3.57
UniProtKB/Swiss-Prot
Q42546, DPNP1_ARATH;  O49623, DPNP2_ARATH;  Q8GY63, DPNP3_ARATH;  
Q84VY5, DPNP4_ARATH;  Q55F34, DPNP_DICDI;  P21327, INPP_BOVIN;  
P49441, INPP_HUMAN;  P49442, INPP_MOUSE;  

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