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ENZYME

ENZYME entry: EC 3.1.3.57

Accepted Name
inositol-1,4-bisphosphate 1-phosphatase
Alternative Name(s)
inositol polyphosphate 1-phosphatase
Reaction catalysed
1D-myo-inositol 1,4-bisphosphate + H2O <=> 1D-myo-inositol 4-phosphate + phosphate
Comment(s)
  • Acts on inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate (forming inositol 3,4-bisphosphate) with similar Vmax for both substrates, but with a 5 times higher affinity for the bisphosphate.
  • Does not act on inositol 1-phosphate, inositol 1,4,5-trisphosphate or inositol 1,3,4,5-tetrakisphosphate.
Cross-references
BRENDA3.1.3.57
EC2PDB3.1.3.57
ExplorEnz3.1.3.57
PRIAM enzyme-specific profiles3.1.3.57
KEGG Ligand Database for Enzyme Nomenclature3.1.3.57
IUBMB Enzyme Nomenclature3.1.3.57
IntEnz3.1.3.57
MEDLINEFind literature relating to 3.1.3.57
MetaCyc3.1.3.57
Rhea expert-curated reactions3.1.3.57
UniProtKB/Swiss-Prot
Q42546, DPNP1_ARATHO49623, DPNP2_ARATHQ8GY63, DPNP3_ARATH
Q84VY5, DPNP4_ARATHQ55F34, DPNP_DICDIC4M4T9, DPNP_ENTH1
P21327, INPP_BOVINC4M633, INPP_ENTH1P49441, INPP_HUMAN
P49442, INPP_MOUSE

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