ENZYME entry: EC 3.1.3.66
Accepted Name |
Phosphatidylinositol-3,4-bisphosphate 4-phosphatase.
|
Alternative Name(s) |
D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase. |
Inositol polyphosphate 4-phosphatase. |
Inositol polyphosphate 4-phosphatase type II. |
Inositol-3,4-bisphosphate 4-phosphatase. |
Phosphoinositide 4-phosphatase. |
Reaction catalysed |
1-phosphatidyl-myo-inositol 3,4-bisphosphate + H(2)O <=> 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate |
Comment(s) |
- Magnesium-independent.
- This enzyme still works when the 2,3-bis(acyloxy)propyl group is
removed, i.e., it hydrolyzes Ins(1,3,4)P(3) to Ins(1,3)P(2).
- It also converts Ins(3,4)P(2) into Ins-3-P.
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Cross-references |
BRENDA | 3.1.3.66 |
EC2PDB | 3.1.3.66 |
ExplorEnz | 3.1.3.66 |
PRIAM enzyme-specific profiles | 3.1.3.66 |
KEGG Ligand Database for Enzyme Nomenclature | 3.1.3.66 |
IUBMB Enzyme Nomenclature | 3.1.3.66 |
IntEnz | 3.1.3.66 |
MEDLINE | Find literature relating to 3.1.3.66 |
MetaCyc | 3.1.3.66 |
Rhea expert-curated reactions | 3.1.3.66 |
UniProtKB/Swiss-Prot |
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