ID   3.1.4.11
DE   phosphoinositide phospholipase C.
AN   1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
AN   inositoltrisphosphohydrolase.
AN   1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase.
AN   monophosphatidylinositol phosphodiesterase.
AN   phosphatidylinositol phospholipase C.
AN   phosphoinositidase C.
AN   PI-PLC.
AN   triphosphoinositide phosphodiesterase.
CA   a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) +
CA   H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol +
CA   H(+).
CC   -!- These enzymes form some of the cyclic phosphate Ins(cyclic
CC       1,2)P(4,5)P2 as well as Ins(1,4,5)P3.
CC   -!- They show activity toward phosphatidylinositol, i.e., the activity of
CC       EC 4.6.1.13 in vitro at high calcium concentration.
DR   Q3KTM2, GDPD5_CHICK;  Q8WTR4, GDPD5_HUMAN;  Q640M6, GDPD5_MOUSE;
DR   P25455, PIP1_DROME ;  P13217, PIPA_DROME ;  O13433, PLC1_CANAX ;
DR   P40977, PLC1_SCHPO ;  P32383, PLC1_YEAST ;  P10894, PLCB1_BOVIN;
DR   Q9NQ66, PLCB1_HUMAN;  Q9Z1B3, PLCB1_MOUSE;  P10687, PLCB1_RAT  ;
DR   Q00722, PLCB2_HUMAN;  A3KGF7, PLCB2_MOUSE;  O89040, PLCB2_RAT  ;
DR   Q01970, PLCB3_HUMAN;  P51432, PLCB3_MOUSE;  Q99JE6, PLCB3_RAT  ;
DR   Q07722, PLCB4_BOVIN;  Q15147, PLCB4_HUMAN;  Q9QW07, PLCB4_RAT  ;
DR   G5EBH0, PLCB_CAEEL ;  Q39032, PLCD1_ARATH;  P10895, PLCD1_BOVIN;
DR   P51178, PLCD1_HUMAN;  Q8R3B1, PLCD1_MOUSE;  P10688, PLCD1_RAT  ;
DR   Q39033, PLCD2_ARATH;  Q56W08, PLCD3_ARATH;  Q8N3E9, PLCD3_HUMAN;
DR   Q8K2J0, PLCD3_MOUSE;  Q944C1, PLCD4_ARATH;  P21671, PLCD4_BOVIN;
DR   Q9BRC7, PLCD4_HUMAN;  Q4R6L3, PLCD4_MACFA;  Q8K3R3, PLCD4_MOUSE;
DR   Q8SPR7, PLCD4_PIG  ;  Q5RET0, PLCD4_PONAB;  Q62711, PLCD4_RAT  ;
DR   Q32NH8, PLCD4_XENLA;  Q944C2, PLCD5_ARATH;  Q8GV43, PLCD6_ARATH;
DR   Q9LY51, PLCD7_ARATH;  Q9STZ3, PLCD8_ARATH;  Q6NMA7, PLCD9_ARATH;
DR   G5EFI8, PLCE1_CAEEL;  Q9P212, PLCE1_HUMAN;  Q8K4S1, PLCE1_MOUSE;
DR   Q99P84, PLCE1_RAT  ;  P08487, PLCG1_BOVIN;  P19174, PLCG1_HUMAN;
DR   Q62077, PLCG1_MOUSE;  P10686, PLCG1_RAT  ;  P16885, PLCG2_HUMAN;
DR   Q8CIH5, PLCG2_MOUSE;  P24135, PLCG2_RAT  ;  Q22070, PLCG_CAEEL ;
DR   Q4KWH8, PLCH1_HUMAN;  Q4KWH5, PLCH1_MOUSE;  O75038, PLCH2_HUMAN;
DR   A2AP18, PLCH2_MOUSE;  Q1RML2, PLCZ1_BOVIN;  Q2VRL0, PLCZ1_CHICK;
DR   Q86YW0, PLCZ1_HUMAN;  Q95JS1, PLCZ1_MACFA;  Q8K4D7, PLCZ1_MOUSE;
DR   Q7YRU3, PLCZ1_PIG  ;  Q5FX52, PLCZ1_RAT  ;  Q02158, PLC_DICDI  ;
DR   A5D6R3, PLD3A_DANRE;
//