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ENZYME

ENZYME entry: EC 3.1.4.12

PURL: https://purl.expasy.org/enzyme/EC/3.1.4.12
Accepted Name
sphingomyelin phosphodiesterase
Alternative Name(s)
acid sphingomyelinase
neutral sphingomyelinase
Reaction catalysed
a sphingomyelin + H2O = phosphocholine + an N-acylsphing-4-enine + H(+)
Comment(s)
Has very little activity on phosphatidylcholine.
Cross-references
BRENDA3.1.4.12
EC2PDB3.1.4.12
ExplorEnz3.1.4.12
KEGG Ligand Database for Enzyme Nomenclature3.1.4.12
IUBMB Enzyme Nomenclature3.1.4.12
MEDLINEFind literature relating to 3.1.4.12
MetaCyc3.1.4.12
Rhea expert-curated reactions3.1.4.12
UniProtKB/Swiss-Prot
Q10916, ASM1_CAEELQ23498, ASM2_CAEELQ9UAY4, ASM3_CAEEL
Q0VD19, ASM_BOVINP17405, ASM_HUMANQ04519, ASM_MOUSE
Q6UWV6, ENPP7_HUMANQ3TIW9, ENPP7_MOUSEQ5EZ72, ENPP7_RAT
Q9NY59, NSMA2_HUMANQ9JJY3, NSMA2_MOUSEO35049, NSMA2_RAT
Q6PFJ7, NSMA3_DANREQ9NXE4, NSMA3_HUMANQ6ZPR5, NSMA3_MOUSE
Q5XHG1, NSMA3_XENLAF1QG30, NSMA5_DANRED6MZJ6, NSMA5_MOUSE
O45870, NSMA_CAEELQ9VZS6, NSMA_DROMEO60906, NSMA_HUMAN
O70572, NSMA_MOUSEQ9ET64, NSMA_RATP09599, PHL1_BACCE
Q72P44, PHL1_LEPICP59115, PHL1_LEPINP11889, PHL2_BACCE
P59116, PHL2_LEPINP33377, PHL3_BACCEQ9RLV9, PHLC_LISIV
P80924, PHLC_STAINP17627, PHL_LEPIRP64744, SMASE_MYCBO
P9WKQ0, SMASE_MYCTOP9WKQ1, SMASE_MYCTUQ1ZXD9, Y8017_DICDI

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-