Expasy logo

ENZYME

ENZYME entry: EC 3.1.4.14

PURL: https://purl.expasy.org/enzyme/EC/3.1.4.14
Accepted Name
[acyl-carrier-protein] phosphodiesterase
Alternative Name(s)
[acyl-carrier-protein] 4'-pantetheine-phosphohydrolase
ACP hydrolyase
ACP phosphodiesterase
Reaction catalysed
holo-[ACP] + H2O = apo-[ACP] + (R)-4'-phosphopantetheine + H(+)
Comment(s)
  • The enzyme cleaves acyl-[acyl-carrier-protein] species with acyl chains of 6-16 carbon atoms although it appears to demonstrate a preference for the unacylated acyl-carrier-protein (ACP) and short- chain ACPs over the medium- and long-chain species.
  • Deletion of the gene encoding this enzyme abolishes ACP prosthetic- group turnover in vivo.
  • Activation of apo-ACP to form the holoenzyme is carried out by EC 2.7.8.7.
Cross-references
BRENDA3.1.4.14
EC2PDB3.1.4.14
ExplorEnz3.1.4.14
KEGG Ligand Database for Enzyme Nomenclature3.1.4.14
IUBMB Enzyme Nomenclature3.1.4.14
MEDLINEFind literature relating to 3.1.4.14
MetaCyc3.1.4.14
Rhea expert-curated reactions3.1.4.14
UniProtKB/Swiss-Prot
A7ZIF6, ACPH_ECO24B7UJM7, ACPH_ECO27B7MD62, ACPH_ECO45
B7L637, ACPH_ECO55Q8XE96, ACPH_ECO57B5Z2W0, ACPH_ECO5E
B7NJ98, ACPH_ECO7IB7MPG5, ACPH_ECO81B7M3P3, ACPH_ECO8A
C4ZTG1, ACPH_ECOBWB1XEZ2, ACPH_ECODHA7ZX55, ACPH_ECOHS
Q0TKN7, ACPH_ECOL5Q8FKC6, ACPH_ECOL6B1J045, ACPH_ECOLC
P21515, ACPH_ECOLIB7N8V6, ACPH_ECOLUB6HZK4, ACPH_ECOSE
B1LJF2, ACPH_ECOSMA4W777, ACPH_ENT38B7LMI3, ACPH_ESCF3
A6T5D6, ACPH_KLEP7B5Y0Y9, ACPH_KLEV3Q6D857, ACPH_PECAS
Q7N0I2, ACPH_PHOLLB5EWT7, ACPH_SALA4A9MM59, ACPH_SALAR
Q57SG0, ACPH_SALCHB5FKQ8, ACPH_SALDCB5QTF2, ACPH_SALEP
B5R6Q5, ACPH_SALG2B4T8P3, ACPH_SALHSB4SWP4, ACPH_SALNS
Q5PFT4, ACPH_SALPAA9MX32, ACPH_SALPBC0Q7S7, ACPH_SALPC
B5BDD0, ACPH_SALPKB4TZH7, ACPH_SALSVQ8XEZ8, ACPH_SALTI
Q7CR41, ACPH_SALTYA8GAM3, ACPH_SERP5B2U407, ACPH_SHIB3
Q325J7, ACPH_SHIBSQ32JF8, ACPH_SHIDSQ83SG7, ACPH_SHIFL
Q3Z505, ACPH_SHISSA1JNT5, ACPH_YERE8A7FLF7, ACPH_YERP3
Q8ZC31, ACPH_YERPEQ66DW7, ACPH_YERPSI6YEE1, PPTH_MYCTU

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-