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ENZYME entry: EC 3.1.4.17

Accepted Name
3',5'-cyclic-nucleotide phosphodiesterase.
Alternative Name(s)
Cyclic AMP phosphodiesterase.
Reaction catalysed
Nucleoside 3',5'-cyclic phosphate + H(2)O <=> nucleoside 5'-phosphate
Comment(s)
Acts on 3',5'-cyclic AMP, 3',5'-cyclic dAMP, 3',5'-cyclic IMP, 3',5'-cyclic GMP and 3',5'-cyclic CMP.
Cross-references
PROSITEPDOC00116 ; PDOC00530
BRENDA3.1.4.17
EC2PDB3.1.4.17
ExplorEnz3.1.4.17
PRIAM enzyme-specific profiles3.1.4.17
KEGG Ligand Database for Enzyme Nomenclature3.1.4.17
IUBMB Enzyme Nomenclature3.1.4.17
IntEnz3.1.4.17
MEDLINEFind literature relating to 3.1.4.17
MetaCyc3.1.4.17
Rhea expert-curated reactions3.1.4.17
UniProtKB/Swiss-Prot
P9WP64, CNPD3_MYCTO;  P9WP65, CNPD3_MYCTU;  Q8YLG0, CNPD3_NOSS1;  
O25683, CNPDE_HELPY;  Q56686, CPDP_ALIFS;  Q8ZD92, CPDP_YERPE;  
Q9Y233, PDE10_HUMAN;  Q8CA95, PDE10_MOUSE;  Q9QYJ6, PDE10_RAT;  
P14100, PDE1A_BOVIN;  P54750, PDE1A_HUMAN;  Q61481, PDE1A_MOUSE;  
Q01061, PDE1B_BOVIN;  Q64395, PDE1B_CRIGR;  Q01064, PDE1B_HUMAN;  
Q01065, PDE1B_MOUSE;  Q01066, PDE1B_RAT;  Q14123, PDE1C_HUMAN;  
Q64338, PDE1C_MOUSE;  Q63421, PDE1C_RAT;  O18696, PDE1_CAEEL;  
P32782, PDE1_CANAX;  B7YZV4, PDE1_DROME;  P36599, PDE1_SCHPO;  
P22434, PDE1_YEAST;  P14099, PDE2A_BOVIN;  O00408, PDE2A_HUMAN;  
Q922S4, PDE2A_MOUSE;  Q01062, PDE2A_RAT;  P30645, PDE2_CAEEL;  
Q14432, PDE3A_HUMAN;  Q9Z0X4, PDE3A_MOUSE;  Q62865, PDE3A_RAT;  
Q13370, PDE3B_HUMAN;  Q61409, PDE3B_MOUSE;  Q63085, PDE3B_RAT;  
Q8I0P7, PDE3_CAEEL;  Q22000, PDE4_CAEEL;  P91119, PDE5_CAEEL;  
Q9N2V9, PDE6_CAEEL;  

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