ENZYME entry: EC 3.1.4.3
Accepted Name |
Phospholipase C.
|
Alternative Name(s) |
Clostridium oedematiens beta- and gamma-toxins. |
Clostridium welchii alpha-toxin. |
Lecithinase C. |
Lipophosphodiesterase I. |
Reaction catalysed |
A phosphatidylcholine + H(2)O <=> 1,2-diacyl-sn-glycerol + phosphocholine |
Cofactor(s) |
Zn(2+).
|
Comment(s) |
- The bacterial enzyme also acts on sphingomyelin and
phosphatidylinositol.
- The enzyme from seminal plasma does not act on phosphatidylinositol.
|
Cross-references |
PROSITE | PDOC00357 |
BRENDA | 3.1.4.3 |
EC2PDB | 3.1.4.3 |
ExplorEnz | 3.1.4.3 |
PRIAM enzyme-specific profiles | 3.1.4.3 |
KEGG Ligand Database for Enzyme Nomenclature | 3.1.4.3 |
IUBMB Enzyme Nomenclature | 3.1.4.3 |
IntEnz | 3.1.4.3 |
MEDLINE | Find literature relating to 3.1.4.3 |
MetaCyc | 3.1.4.3 |
Rhea expert-curated reactions | 3.1.4.3 |
UniProtKB/Swiss-Prot |
Q9SRQ7, NPC4_ARATH; | Q9S816, NPC5_ARATH; | P9WIB4, PHLA_MYCTO; |
P9WIB5, PHLA_MYCTU; | P9WIB2, PHLB_MYCTO; | P9WIB3, PHLB_MYCTU; |
P0C216, PHLC1_CLOPE; | P09598, PHLC_BACCE; | P59026, PHLC_CLOHA; |
Q46150, PHLC_CLONO; | Q0TV31, PHLC_CLOP1; | Q9RF12, PHLC_CLOPF; |
P33378, PHLC_LISMO; | P9WIB0, PHLC_MYCTO; | P9WIB1, PHLC_MYCTU; |
Q8VUZ6, PHLC_PAESO; | P20419, PHLC_PARBF; | P06200, PHLC_PSEAE; |
Q2FWP1, PHLC_STAA8; | Q5HEI1, PHLC_STAAC; | P09978, PHLC_STAAU; |
P33376, PHLD_BACCE; | P0A5R9, PHLD_MYCBO; | P9WIA8, PHLD_MYCTO; |
P9WIA9, PHLD_MYCTU; | Q9RGS8, PHLN_BURPS; | P15713, PHLN_PSEAE; |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.1.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-