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ENZYME

ENZYME entry: EC 3.1.4.3

Accepted Name
phospholipase C
Alternative Name(s)
Clostridium oedematiens beta- and gamma-toxins
Clostridium welchii alpha-toxin
lecithinase C
lipophosphodiesterase I
Reaction catalysed
a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O <=> a 1,2-diacyl-sn-glycerol + H(+) + phosphocholine
Comment(s)
  • The bacterial enzyme also acts on sphingomyelin and phosphatidylinositol.
  • The enzyme from seminal plasma does not act on phosphatidylinositol.
Cross-references
BRENDA3.1.4.3
EC2PDB3.1.4.3
ExplorEnz3.1.4.3
PRIAM enzyme-specific profiles3.1.4.3
KEGG Ligand Database for Enzyme Nomenclature3.1.4.3
IUBMB Enzyme Nomenclature3.1.4.3
IntEnz3.1.4.3
MEDLINEFind literature relating to 3.1.4.3
MetaCyc3.1.4.3
Rhea expert-curated reactions3.1.4.3
UniProtKB/Swiss-Prot
Q0VD19, ASM_BOVINP17405, ASM_HUMANQ04519, ASM_MOUSE
Q7D5F9, LIPF_MYCTOO06350, LIPF_MYCTUQ9SRQ7, NPC4_ARATH
Q9S816, NPC5_ARATHP9WIB4, PHLA_MYCTOP9WIB5, PHLA_MYCTU
P9WIB2, PHLB_MYCTOP9WIB3, PHLB_MYCTUP0C216, PHLC1_CLOPE
P09598, PHLC_BACCEP59026, PHLC_CLOHAQ46150, PHLC_CLONO
Q0TV31, PHLC_CLOP1Q9RF12, PHLC_CLOPFP33378, PHLC_LISMO
P9WIB0, PHLC_MYCTOP9WIB1, PHLC_MYCTUQ8VUZ6, PHLC_PAESO
P20419, PHLC_PARBFP06200, PHLC_PSEAEQ2FWP1, PHLC_STAA8
Q5HEI1, PHLC_STAACP09978, PHLC_STAAUP33376, PHLD_BACCE
P0A5R9, PHLD_MYCBOP9WIA8, PHLD_MYCTOP9WIA9, PHLD_MYCTU
Q9RGS8, PHLN_BURPSP15713, PHLN_PSEAE

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