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ENZYME entry: EC 3.1.4.41

Accepted Name
sphingomyelin phosphodiesterase D.
Reaction catalysed
a sphingomyelin + H2O <=> an N-acylsphing-4-enine 1-phosphate + choline + H(+)
Comment(s)
Does not act on phosphatidylcholine, but hydrolyzes 2-lysophosphatidylcholine to choline and 2-lysophosphatidate.
Cross-references
BRENDA3.1.4.41
EC2PDB3.1.4.41
ExplorEnz3.1.4.41
PRIAM enzyme-specific profiles3.1.4.41
KEGG Ligand Database for Enzyme Nomenclature3.1.4.41
IUBMB Enzyme Nomenclature3.1.4.41
IntEnz3.1.4.41
MEDLINEFind literature relating to 3.1.4.41
MetaCyc3.1.4.41
Rhea expert-curated reactions3.1.4.41
UniProtKB/Swiss-Prot
Q59121, PLD_ARCHD;  P20626, PLD_CORPS;  Q59332, PLD_CORUL;  
C0NUU1, SMD_AJECG;  D4AZV8, SMD_ARTBC;  B8NQ51, SMD_ASPFN;  
J3K844, SMD_COCIM;  C0S3M9, SMD_PARBP;  F2SCC4, SMD_TRIRC;  
C4JUE5, SMD_UNCRE;  

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