ENZYME entry: EC 3.1.4.54
Accepted Name |
N-acetylphosphatidylethanolamine-hydrolyzing phospholipase D.
|
Alternative Name(s) |
Anandamide-generating phospholipase D. |
N-acyl phosphatidylethanolamine phospholipase D. |
Reaction catalysed |
An N-acylphosphatidylethanolamine + H(2)O <=> an N-acylethanolamine + a 1,2-diacylglycerol 3-phosphate |
Cofactor(s) |
Zn(2+).
|
Comment(s) |
- This enzyme is involved in the biosynthesis of anandamide.
- It does not hydrolyze phosphatidylcholine and
phosphatidylethanolamine.
- No transphosphatidation.
|
Cross-references |
BRENDA | 3.1.4.54 |
EC2PDB | 3.1.4.54 |
ExplorEnz | 3.1.4.54 |
PRIAM enzyme-specific profiles | 3.1.4.54 |
KEGG Ligand Database for Enzyme Nomenclature | 3.1.4.54 |
IUBMB Enzyme Nomenclature | 3.1.4.54 |
IntEnz | 3.1.4.54 |
MEDLINE | Find literature relating to 3.1.4.54 |
MetaCyc | 3.1.4.54 |
Rhea expert-curated reactions | 3.1.4.54 |
UniProtKB/Swiss-Prot |
|
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