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ENZYME entry: EC 3.1.4.56

Accepted Name
7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase.
Reaction catalysed
  • 7,8-dihydroneopterin 2',3'-cyclic phosphate + H(2)O <=> 7,8-dihydroneopterin 3'-phosphate
  • 7,8-dihydroneopterin 2',3'-cyclic phosphate + H(2)O <=> 7,8-dihydroneopterin 2'-phosphate
Cofactor(s)
Fe(2+); Zn(2+).
Comment(s)
  • Hydrolyzes 7,8-dihydroneopterin 2',3'-cyclic phosphate, a step in tetrahydromethanopterin biosynthesis.
  • In vitro the enzyme forms 7,8-dihydroneopterin 2'-phosphate and 7,8- dihydroneopterin 3'-phosphate at a ratio of 4:1.
Cross-references
BRENDA3.1.4.56
EC2PDB3.1.4.56
ExplorEnz3.1.4.56
PRIAM enzyme-specific profiles3.1.4.56
KEGG Ligand Database for Enzyme Nomenclature3.1.4.56
IUBMB Enzyme Nomenclature3.1.4.56
IntEnz3.1.4.56
MEDLINEFind literature relating to 3.1.4.56
MetaCyc3.1.4.56
Rhea expert-curated reactions3.1.4.56
UniProtKB/Swiss-Prot
Q58247, MPTB_METJA

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