ENZYME entry: EC 3.1.4.58
Accepted Name |
RNA 2',3'-cyclic 3'-phosphodiesterase.
|
Reaction catalysed |
(Ribonucleotide)(n)-2',3'-cyclic phosphate + H(2)O <=> (ribonucleotide)(n)-2'-phosphate |
Comment(s) |
- The enzyme hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA
2'-phosphomonoester.
- In vitro the enzyme can also ligate tRNA molecules with 2',3'-cyclic
phosphate to tRNA with 5'-hydroxyl termini, forming a 2'-5'
phosphodiester linkage.
- However, the ligase activity is unlikely to be relevant in vivo.
|
Cross-references |
BRENDA | 3.1.4.58 |
EC2PDB | 3.1.4.58 |
ExplorEnz | 3.1.4.58 |
PRIAM enzyme-specific profiles | 3.1.4.58 |
KEGG Ligand Database for Enzyme Nomenclature | 3.1.4.58 |
IUBMB Enzyme Nomenclature | 3.1.4.58 |
IntEnz | 3.1.4.58 |
MEDLINE | Find literature relating to 3.1.4.58 |
MetaCyc | 3.1.4.58 |
Rhea expert-curated reactions | 3.1.4.58 |
UniProtKB/Swiss-Prot |
Q9YB03, THPR_AERPE; | O66967, THPR_AQUAE; | O28125, THPR_ARCFU; |
O34570, THPR_BACSU; | P37025, THPR_ECOLI; | Q45633, THPR_GEOSE; |
Q58963, THPR_METJA; | O26683, THPR_METTH; | Q8U4Q3, THPR_PYRFU; |
O57823, THPR_PYRHO; | Q9X2H4, THPR_THEMA; | Q5SHB1, THPR_THET8; |
|
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