ID   3.1.4.59
DE   cyclic-di-AMP phosphodiesterase.
CA   3',3'-c-di-AMP + H2O = 5'-O-phosphonoadenylyl-(3'->5')-adenosine + H(+).
CC   -!- The enzyme, described from Gram-positive bacteria, degrades the
CC       second messenger cyclic di-3',5'-adenylate.
CC   -!- It is a membrane-bound protein that contains a cytoplasmic facing
CC       Per-Arnt-Sim (PAS) domain, a modified GGDEF domain, and a DHH/DHHA1
CC       domain, which confers the phosphodiesterase activity.
CC   -!- Activity requires Mn(2+) and is inhibited by pApA.
DR   P37484, GDPP_BACSU ;  A4ITV2, GDPP_GEOTN ;  A0A0H3GCG4, PDEA_LISM4 ;
DR   P46344, PGPH_BACSU ;  A0A0H3GGY3, PGPH_LISM4 ;
//