ID   3.1.4.60
DE   pApA phosphodiesterase.
AN   pApA hydrolase.
CA   5'-O-phosphonoadenylyl-(3'->5')-adenosine + H2O = 2 AMP + H(+).
CC   -!- The enzyme, characterized from the Gram-positive bacterium
CC       Staphylococcus aureus, is a cytoplasmic protein that contains a
CC       DHH/DHHA1 domain.
CC   -!- It can act on cyclic di-3',5'-adenylate with a much lower activity
CC       (cf. EC 3.1.4.59).
CC   -!- Activity requires Mn(2+) and is inhibited by ppGpp.
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