ID   3.1.6.19
DE   (R)-specific secondary-alkylsulfatase (type III).
AN   (R)-specific sec-alkylsulfatase.
AN   (R)-specific secondary-alkylsulfatase.
AN   sec-alkylsulfatase.
CA   an (R)-secondary-alkyl sulfate + H2O = an (S)-secondary-alcohol +
CA   sulfate.
CC   -!- Sulfatase enzymes are classified as type I, in which the key
CC       catalytic residue is 3-oxo-L-alanine, type II, which are non-heme
CC       iron-dependent dioxygenases, or type III, whose catalytic domain
CC       adopts a metallo-beta-lactamase fold and binds two zinc ions as
CC       cofactors.
CC   -!- This enzyme belongs to the type III sulfatase family.
CC   -!- The enzyme from the bacterium Rhodococcus ruber prefers linear
CC       secondary-alkyl sulfate esters, particularly octan-2-yl, octan-3-yl,
CC       and octan-4-yl sulfates.
CC   -!- The enzyme from the bacterium Pseudomonas sp. DSM6611 utilizes a
CC       range of secondary-alkyl sulfate esters bearing aromatic, olefinic
CC       and acetylenic moieties.
CC   -!- Hydrolysis proceeds through inversion of the configuration at the
CC       stereogenic carbon atom, resulting in perfect enantioselectivity. cf.
CC       EC 1.14.11.77 and EC 3.1.6.1.
DR   F8KAY7, RSAKS_PSESP;
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