Home  |  Contact

ENZYME entry: EC 3.13.1.8

Accepted Name
S-adenosyl-L-methionine hydrolase (adenosine-forming).
Alternative Name(s)
SAM hydroxide adenosyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + H(2)O <=> adenosine + L-methionine
Comment(s)
  • The enzyme, found in bacteria and archaea, catalyzes a nucleophilic attack of water at the C5' carbon of S-adenosyl-L-methionine to generate adenosine and L-methionine.
  • May be involved in regulating SAM levels in the cell.
  • Cf. EC 3.3.1.2.
Cross-references
BRENDA3.13.1.8
EC2PDB3.13.1.8
ExplorEnz3.13.1.8
PRIAM enzyme-specific profiles3.13.1.8
KEGG Ligand Database for Enzyme Nomenclature3.13.1.8
IUBMB Enzyme Nomenclature3.13.1.8
IntEnz3.13.1.8
MEDLINEFind literature relating to 3.13.1.8
MetaCyc3.13.1.8
Rhea expert-curated reactions3.13.1.8
UniProtKB/Swiss-Prot
O58212, SAMHD_PYRHO;  A8M783, SAMHD_SALAI;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.13.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.13.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-