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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.2.1.107

Accepted Name
Protein-glucosylgalactosylhydroxylysine glucosidase.
Reaction catalysed
Protein alpha-D-glucosyl-(1->2)-beta-D-galactosyl-L-hydroxylysine + H(2)O <=> D-glucose + protein beta-D-galactosyl-L-hydroxylysine
Comment(s)
  • The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins.
  • Acetylation of the epsilon-amino group of the glycosylated hydroxylysine abolishes activity.
Cross-references
BRENDA3.2.1.107
EC2PDB3.2.1.107
ExplorEnz3.2.1.107
PRIAM enzyme-specific profiles3.2.1.107
KEGG Ligand Database for Enzyme Nomenclature3.2.1.107
IUBMB Enzyme Nomenclature3.2.1.107
IntEnz3.2.1.107
MEDLINEFind literature relating to 3.2.1.107
MetaCyc3.2.1.107
UniProtKB/Swiss-Prot
F1NZI4, PGGHG_CHICK;  A0JMP0, PGGHG_DANRE;  Q54KX5, PGGHG_DICDI;  
Q32M88, PGGHG_HUMAN;  Q8BP56, PGGHG_MOUSE;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-