ID   3.2.1.130
DE   glycoprotein endo-alpha-1,2-mannosidase.
AN   endo-alpha-D-mannosidase.
CA   H2O + N-{alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-
CA   Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-
CA   Man-(1->6)]-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-
CA   GlcNAc}-L-asparaginyl-[protein] = alpha-D-glucosyl-(1->3)-D-mannopyranose
CA   + N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-
CA   D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-
CA   beta-D-Man-(1->4)-beta-D-GlaNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-
CA   [protein] (N-glucan mannose isomer 8A1,2,3B1,2).
CC   -!- The enzyme catalyzes the hydrolysis of the terminal alpha-D-glucosyl-
CC       (1->3)-D-mannosyl unit from the GlcMan9(GlcNAc)2 oligosaccharide
CC       component of N-glucosylated proteins during their processing in the
CC       Golgi apparatus.
DR   Q5SRI9, MANEA_HUMAN;  Q6NXH2, MANEA_MOUSE;  Q5RD93, MANEA_PONAB;
DR   Q5GF25, MANEA_RAT  ;  Q6DE40, MANEA_XENLA;
//