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ENZYME entry: EC 3.2.1.15

Accepted Name
Endo-polygalacturonase.
Alternative Name(s)
Pectin depolymerase.
Pectinase.
Polygalacturonase.
Reaction catalysed
(1,4-alpha-D-galacturonosyl)(n+m) + H(2)O <=> (1,4-alpha-D-galacturonosyl)(n) + (1,4-alpha-D-galacturonosyl)(m)
Comment(s)
  • The enzyme catalyzes the random hydrolysis of (1->4)-alpha-D- galactosiduronic linkages in pectate and other galacturonans.
  • Different forms of the enzyme have different tolerances to methyl esterification of the substrate.
Cross-references
PROSITEPDOC00415
BRENDA3.2.1.15
EC2PDB3.2.1.15
ExplorEnz3.2.1.15
PRIAM enzyme-specific profiles3.2.1.15
KEGG Ligand Database for Enzyme Nomenclature3.2.1.15
IUBMB Enzyme Nomenclature3.2.1.15
IntEnz3.2.1.15
MEDLINEFind literature relating to 3.2.1.15
MetaCyc3.2.1.15
Rhea expert-curated reactions3.2.1.15
UniProtKB/Swiss-Prot
O23147, ADPG1_ARATH;  Q8RY29, ADPG2_ARATH;  O74213, PGLR1_ASPAC;  
A1CIV8, PGLR1_ASPCL;  B8N8M2, PGLR1_ASPFN;  A2QAH3, PGLR1_ASPNC;  
P26213, PGLR1_ASPNG;  Q2UHL4, PGLR1_ASPOR;  Q0CMU3, PGLR1_ASPTN;  
Q00446, PGLR1_COLLN;  P18192, PGLR1_PECCC;  Q9Y834, PGLR1_PENOL;  
Q12708, PGLR1_SCLSC;  Q70HJ4, PGLR2_ASPAC;  Q9P359, PGLR2_ASPAW;  
Q8NK98, PGLR2_ASPKW;  P26214, PGLR2_ASPNA;  A2R5S4, PGLR2_ASPNC;  
P0CU55, PGLR2_ASPNG;  P0CU54, PGLR2_ASPTU;  Q7M1E7, PGLR2_CHAOB;  
P43212, PGLR2_CRYJA;  Q9FY19, PGLR2_JUNAS;  P26509, PGLR2_PECPM;  
Q9Y833, PGLR2_PENOL;  Q9LW07, PGLR3_ARATH;  Q949Z1, PGLR4_ARATH;  
Q94AJ5, PGLR5_ARATH;  O22818, PGLR6_ARATH;  Q9P358, PGLRA_ASPAW;  
P41749, PGLRA_ASPFA;  B0Y4Z4, PGLRA_ASPFC;  Q4WQT2, PGLRA_ASPFU;  
Q8NK99, PGLRA_ASPKW;  A2R8F8, PGLRA_ASPNC;  Q9P4W4, PGLRA_ASPNG;  
P49575, PGLRA_ASPPA;  A1CVV8, PGLRA_NEOFI;  P41750, PGLRB_ASPFA;  
B0YAH0, PGLRB_ASPFC;  B8N7Z8, PGLRB_ASPFN;  Q4WBE1, PGLRB_ASPFU;  
Q1HAY5, PGLRB_ASPKA;  A2QCV8, PGLRB_ASPNC;  Q9P4W3, PGLRB_ASPNG;  
P35335, PGLRB_ASPOR;  Q5B508, PGLRB_EMENI;  A1DAQ2, PGLRB_NEOFI;  
Q70HJ3, PGLRC_ASPAC;  A2QL39, PGLRC_ASPNC;  Q12554, PGLRC_ASPNG;  
B8MW78, PGLRD_ASPFN;  A2QTU0, PGLRD_ASPNC;  Q9P4W2, PGLRD_ASPNG;  
Q2UT29, PGLRD_ASPOR;  Q5AYH4, PGLRD_EMENI;  A1DBR6, PGLRD_NEOFI;  
A2QBB6, PGLRE_ASPNC;  O42809, PGLRE_ASPNG;  P35336, PGLR_ACTDE;  
B0XPA1, PGLR_ASPFC;  Q4WR80, PGLR_ASPFU;  P35337, PGLR_BRANA;  
P26215, PGLR_COCCA;  C0HKB1, PGLR_CUPSE;  P81179, PGLR_DIAAB;  
Q5ATQ3, PGLR_EMENI;  Q07181, PGLR_GIBFU;  Q39766, PGLR_GOSBA;  
Q39786, PGLR_GOSHI;  P48978, PGLR_MALDO;  Q40312, PGLR_MEDSA;  
A1D145, PGLR_NEOFI;  Q9Y718, PGLR_PENDI;  O59925, PGLR_PENEN;  
O93883, PGLR_PENGR;  O42824, PGLR_PENJA;  Q02096, PGLR_PERAE;  
O97400, PGLR_PHACE;  P48979, PGLR_PRUPE;  P20041, PGLR_RALSL;  
P58598, PGLR_RALSO;  P27644, PGLR_RHIRD;  P05117, PGLR_SOLLC;  
Q05967, PGLR_TOBAC;  A7PZL3, PGLR_VITVI;  P47180, PGLR_YEAST;  
Q9SFB7, QRT2_ARATH;  O49432, QRT3_ARATH;  

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