ID 3.2.1.163 DE 1,6-alpha-D-mannosidase. CA Hydrolysis of the 1,6-linked alpha-D-mannose residues in alpha-D-Manp- CA (1->6)-D-Manp. CC -!- Specific for (1->6)-linked mannobiose and has no activity toward any CC other linkages, or toward p-nitrophenyl-alpha-D-mannopyranoside or CC mannan from Saccharomyces cerevisiae (baker's yeast). CC -!- It is strongly inhibited by Mn(2+) but does not require Ca(2+) or any CC other metal cofactor for activity. //