ENZYME entry: EC 3.2.1.179
| Accepted Name |
|---|
| Gellan tetrasaccharide unsaturated glucuronosyl hydrolase.
|
| Alternative Name(s) |
|---|
| Gellan tetrasaccharide unsaturated glucuronyl hydrolase. |
| Unsaturated glucuronyl hydrolase. |
| Reaction catalysed |
|---|
| Beta-D-4-deoxy-Delta(4)-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp + H(2)O <=> 5-dehydro-4-deoxy-D-glucuronate + beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp |
| Comment(s) |
|---|
- The enzyme releases 4-deoxy-4(5)-unsaturated D-glucuronic acid from
oligosaccharides produced by polysaccharide lyases, e.g. the
tetrasaccharide beta-D-4-deoxy-Delta(4)-GlcAp-(1->4)-beta-D-Glcp-
(1->4)-alpha-L-Rhap-(1->3)-D-Glcp produced by EC 4.2.2.25.
- The enzyme can also hydrolyze unsaturated chondroitin and hyaluronate
disaccharides (beta-D-4-deoxy-Delta(4)-GlcAp-(1->3)-beta-D-GalNAc,
beta-D-4-deoxy-Delta(4)-GlcAp-(1->3)-beta-D-GalNAc6S, beta-D-4-deoxy-
Delta(4)-GlcAp2S-(1->3)-beta-D-GalNAc, beta-D-4-deoxy-Delta(4)-GlcAp-
(1->3)-beta-D-GlcNAc), preferring the unsulfated disaccharides to the
sulfated disaccharides.
|
| Cross-references |
|---|
| BRENDA | 3.2.1.179 |
| EC2PDB | 3.2.1.179 |
| ExplorEnz | 3.2.1.179 |
| PRIAM enzyme-specific profiles | 3.2.1.179 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.2.1.179 |
| IUBMB Enzyme Nomenclature | 3.2.1.179 |
| IntEnz | 3.2.1.179 |
| MEDLINE | Find literature relating to 3.2.1.179 |
| MetaCyc | 3.2.1.179 |
| Rhea expert-curated reactions | 3.2.1.179 |
| UniProtKB/Swiss-Prot |
|
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