A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.2.1.179
Accepted Name |
Gellan tetrasaccharide unsaturated glucuronosyl hydrolase.
|
Alternative Name(s) |
Gellan tetrasaccharide unsaturated glucuronyl hydrolase. |
Unsaturated glucuronyl hydrolase. |
Reaction catalysed |
Beta-D-4-deoxy-Delta(4)-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp + H(2)O <=> 5-dehydro-4-deoxy-D-glucuronate + beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp |
Comment(s) |
- The enzyme releases 4-deoxy-4(5)-unsaturated D-glucuronic acid from
oligosaccharides produced by polysaccharide lyases, e.g. the
tetrasaccharide beta-D-4-deoxy-Delta(4)-GlcAp-(1->4)-beta-D-Glcp-
(1->4)-alpha-L-Rhap-(1->3)-D-Glcp produced by EC 4.2.2.25.
- The enzyme can also hydrolyze unsaturated chondroitin and hyaluronate
disaccharides (beta-D-4-deoxy-Delta(4)-GlcAp-(1->3)-beta-D-GalNAc,
beta-D-4-deoxy-Delta(4)-GlcAp-(1->3)-beta-D-GalNAc6S, beta-D-4-deoxy-
Delta(4)-GlcAp2S-(1->3)-beta-D-GalNAc, beta-D-4-deoxy-Delta(4)-GlcAp-
(1->3)-beta-D-GlcNAc), preferring the unsulfated disaccharides to the
sulfated disaccharides.
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Cross-references |
BRENDA | 3.2.1.179 |
EC2PDB | 3.2.1.179 |
ExplorEnz | 3.2.1.179 |
PRIAM enzyme-specific profiles | 3.2.1.179 |
KEGG Ligand Database for Enzyme Nomenclature | 3.2.1.179 |
IUBMB Enzyme Nomenclature | 3.2.1.179 |
IntEnz | 3.2.1.179 |
MEDLINE | Find literature relating to 3.2.1.179 |
MetaCyc | 3.2.1.179 |
UniProtKB/Swiss-Prot |
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UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
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