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ENZYME entry: EC 3.2.1.193

Accepted Name
Ginsenosidase type I.
Reaction catalysed
  • A protopanaxadiol-type ginsenoside with two glucosyl residues at position 3 + H(2)O <=> a protopanaxadiol-type ginsenoside with one glucosyl residue at position 3 + D-glucopyranose
  • A protopanaxadiol-type ginsenoside with one glucosyl residue at position 3 + H(2)O <=> a protopanaxadiol-type ginsenoside with no glycosidic modifications at position 3 + D-glucopyranose
  • A protopanaxadiol-type ginsenoside with two glycosyl residues at position 20 + H(2)O <=> a protopanaxadiol-type ginsenoside with a single glucosyl residue at position 20 + a monosaccharide
Comment(s)
  • The enzyme hydrolyzes the 3-O-beta-D-(1->2)-glucosidic bond, the 3-O- beta-D-glucopyranosyl bond and the 20-O-beta-D-(1->6)-glycosidic bond of protopanaxadiol-type ginsenosides.
  • It usually leaves a single glucosyl residue attached at position 20 and one or no glucosyl residues at position 3.
  • Starting with a ginsenoside that is glycosylated at both positions (e.g. ginsenoside Rb1, Rb2, Rb3, Rc or Rd), the most common products are ginsenoside F2 and ginsenoside C-K, with low amounts of ginsenoside Rh2.
Cross-references
BRENDA3.2.1.193
EC2PDB3.2.1.193
ExplorEnz3.2.1.193
PRIAM enzyme-specific profiles3.2.1.193
KEGG Ligand Database for Enzyme Nomenclature3.2.1.193
IUBMB Enzyme Nomenclature3.2.1.193
IntEnz3.2.1.193
MEDLINEFind literature relating to 3.2.1.193
MetaCyc3.2.1.193
Rhea expert-curated reactions3.2.1.193

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-