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ENZYME entry: EC 3.2.1.211

Accepted Name
Endo-(1->3)-fucoidanase.
Alternative Name(s)
Alpha-L-fucosidase.
Poly(1,3-alpha-L-fucoside-2/4-sulfate) glycanohydrolase.
Reaction catalysed
Endohydrolysis of (1->3)-alpha-L-fucoside linkages in fucan
Comment(s)
  • The enzyme specifically hydrolyzes (1->3)-alpha-L-fucoside linkages in fucan.
  • Fucans are found mainly in different species of seaweed and are sulfated polysaccharides with a backbone of (1->3)-linked or alternating (1->3)- and (1->4)-linked alpha-L-fucopyranosyl residues.
  • In the literature, the sulfated polysaccharides are often called fucoidans.
  • Fucoidans include polysaccharides with a relatively low proportion of fucose and some polysaccharides that have a backbone composed of other saccharides with fucose in the branching side chains.
  • The sulfation of the alpha-L-fucopyranosyl residues may occur at positions 2 and 4.
  • The enzyme degrades fucan to sulfated alpha-L-fucooligosaccharides but neither L-fucose nor small fucooligosaccharides are produced.
  • Formerly EC 3.2.1.44.
Cross-references
BRENDA3.2.1.211
EC2PDB3.2.1.211
ExplorEnz3.2.1.211
PRIAM enzyme-specific profiles3.2.1.211
KEGG Ligand Database for Enzyme Nomenclature3.2.1.211
IUBMB Enzyme Nomenclature3.2.1.211
IntEnz3.2.1.211
MEDLINEFind literature relating to 3.2.1.211
MetaCyc3.2.1.211

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-