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ENZYME entry: EC 3.2.1.212

Accepted Name
endo-(1->4)-fucoidanase
Alternative Name(s)
alpha-L-fucosidase
poly(1,4-alpha-L-fucoside-2/3-sulfate) glycanohydrolase
Reaction catalysed
endohydrolysis of (1->4)-alpha-L-fucoside linkages in fucan
Comment(s)
The enzyme specifically hydrolyzes (1->4)-alpha-L-fucoside linkages in fucan. Fucans are found mainly in different species of seaweed and are sulfated polysaccharides with a backbone of (1->3)-linked or alternating (1->3)- and (1->4)-linked alpha-L-fucopyranosyl residues. In the literature, the sulfated polysaccharides are often called fucoidans. Fucoidans include polysaccharides with a relatively low proportion of fucose and some polysaccharides that have a backbone composed of other saccharides with fucose in the branching side chains. The sulfation of the alpha-L-fucopyranosyl residues may occur at positions 2 and 3. The enzyme degrades fucan to sulfated alpha-L-fucooligosaccharides but neither L-fucose nor small fucooligosaccharides are produced. Formerly EC 3.2.1.44.
Cross-references
BRENDA	3.2.1.212
EC2PDB	3.2.1.212
ExplorEnz	3.2.1.212
PRIAM enzyme-specific profiles	3.2.1.212
KEGG Ligand Database for Enzyme Nomenclature	3.2.1.212
IUBMB Enzyme Nomenclature	3.2.1.212
IntEnz	3.2.1.212
MEDLINE	Find literature relating to 3.2.1.212
MetaCyc	3.2.1.212
Rhea expert-curated reactions	3.2.1.212