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ENZYME entry: EC 3.2.1.22

Accepted Name
Alpha-galactosidase.
Alternative Name(s)
Melibiase.
Reaction catalysed
Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids
Cofactor(s)
Mg(2+); NAD(+).
Comment(s)
Also hydrolyzes alpha-D-fucosides.
Cross-references
PROSITEPDOC00443 ; PDOC01027
BRENDA3.2.1.22
EC2PDB3.2.1.22
ExplorEnz3.2.1.22
PRIAM enzyme-specific profiles3.2.1.22
KEGG Ligand Database for Enzyme Nomenclature3.2.1.22
IUBMB Enzyme Nomenclature3.2.1.22
IntEnz3.2.1.22
MEDLINEFind literature relating to 3.2.1.22
MetaCyc3.2.1.22
Rhea expert-curated reactions3.2.1.22
UniProtKB/Swiss-Prot
Q9ALJ4, AGAA_GEOSE;  Q9FT97, AGAL1_ARATH;  P43467, AGAL1_PEDPE;  
Q8RX86, AGAL2_ARATH;  Q92457, AGAL2_HYPJE;  P43469, AGAL2_PEDPE;  
Q8VXZ7, AGAL3_ARATH;  Q92451, AGAL3_HYPJE;  C8VJZ7, AGAL8_EMENI;  
A1CBW8, AGALA_ASPCL;  B8MWJ5, AGALA_ASPFN;  Q4WVZ3, AGALA_ASPFU;  
A2QL72, AGALA_ASPNC;  P28351, AGALA_ASPNG;  Q2UT06, AGALA_ASPOR;  
Q0CPK2, AGALA_ASPTN;  A1DDD8, AGALA_NEOFI;  A1C5D3, AGALB_ASPCL;  
B0Y224, AGALB_ASPFC;  B8N306, AGALB_ASPFN;  Q4WE86, AGALB_ASPFU;  
A2QEJ9, AGALB_ASPNC;  Q9Y865, AGALB_ASPNG;  Q2UJ97, AGALB_ASPOR;  
Q5AVQ6, AGALB_EMENI;  A1D0A3, AGALB_NEOFI;  O94221, AGALB_PENSI;  
A7XZT2, AGALB_TALEM;  B8NWY6, AGALC_ASPFN;  Q9UUZ4, AGALC_ASPNG;  
Q2TW69, AGALC_ASPOR;  Q0CVH2, AGALC_ASPTN;  Q5AU92, AGALC_EMENI;  
B0YEK2, AGALD_ASPFC;  B8N7Z0, AGALD_ASPFN;  A4DA70, AGALD_ASPFU;  
A2R2S6, AGALD_ASPNC;  Q2UI87, AGALD_ASPOR;  Q0CVX4, AGALD_ASPTN;  
Q5AX28, AGALD_EMENI;  A1D9S3, AGALD_NEOFI;  Q0CEF5, AGALG_ASPTN;  
Q5ARP5, AGALG_EMENI;  O34645, AGAL_BACSU;  Q8A6L0, AGAL_BACTN;  
P86073, AGAL_CAPAA;  B3PGJ1, AGAL_CELJU;  Q42656, AGAL_COFAR;  
P14749, AGAL_CYATE;  Q55B10, AGAL_DICDI;  P06720, AGAL_ECOLI;  
P06280, AGAL_HUMAN;  P51569, AGAL_MOUSE;  Q9FXT4, AGAL_ORYSJ;  
Q9X4Y0, AGAL_RHIME;  Q97U94, AGAL_SACS2;  P30877, AGAL_SALTY;  
Q9URZ0, AGAL_SCHPO;  D7CFN7, AGAL_STRBB;  P27756, AGAL_STRMU;  
G4FEF4, AGAL_THEMA;  G4T4R7, AGASK_RUMGN;  B2UL12, GLAA_AKKM8;  
Q5L7M8, GLAA_BACFN;  Q64MU6, GLAA_BACFR;  Q8A2Z5, GLAA_BACTN;  
B1KD83, GLAA_SHEWM;  Q826C5, GLAA_STRAW;  B1V8K7, GLAA_STRGU;  
A6KWM0, GLAB1_PHOV8;  A6L2M8, GLAB2_PHOV8;  B2UNU8, GLAB_AKKM8;  
Q5LGZ8, GLAB_BACFN;  Q64XV2, GLAB_BACFR;  Q89ZX0, GLAB_BACTN;  
A6LFT2, GLAB_PARD8;  P04824, MEL1_YEASX;  P41945, MEL2_YEASX;  
P41946, MEL5_YEASX;  P41947, MEL6_YEASX;  G1UB44, MELA_LACAC;  
Q99172, MEL_LACCI;  Q03647, MEL_SACCA;  Q11129, MEL_SACMI;  
Q09187, MEL_SACPA;  Q9UVD6, MEL_TORDE;  Q9P4V4, MEL_ZYGMR;  
P16551, RAFA_ECOLX;  

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