Expasy logo

ENZYME

ENZYME entry: EC 3.2.1.35

PURL: https://purl.expasy.org/enzyme/EC/3.2.1.35
Accepted Name
hyaluronoglucosaminidase
Alternative Name(s)
chondroitinase
chondroitinase I
hyaluronidase
hyaluronoglucosidase
Reaction catalysed
Random hydrolysis of (1->4)-linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate
Comment(s)
  • Also hydrolyzes 1,4-beta-D-glycosidic linkages between N-acetyl- galactosamine or N-acetylgalactosamine sulfate and glucuronic acid in chondroitin, chondroitin 4- and 6-sulfates, and dermatan.
  • Formerly EC 3.2.1.34.
Cross-references
Rhea expert-curated reactions3.2.1.35
ExplorEnz3.2.1.35
IUBMB Enzyme Nomenclature3.2.1.35
UniProtKB/Swiss-Prot
A3KPQ7, CEIP2_DANREQ9UHN6, CEIP2_HUMANQ5FWI3, CEIP2_MOUSE
Q8WUJ3, CEMIP_HUMANQ8BI06, CEMIP_MOUSEP50828, HEMO_PIG
A3QVN9, HYAL1_BITARQ5E985, HYAL1_BOVINA3QVN3, HYAL1_CERCE
A0A1L4BJ83, HYAL1_HEMLEQ12794, HYAL1_HUMANQ91ZJ9, HYAL1_MOUSE
P86100, HYAL1_OLIMRQ6RHW4, HYAL1_PIGQ76HN1, HYAL1_RAT
A0A0C9RFM5, HYAL1_TITBAP85841, HYAL1_TITSEA3QVP0, HYAL2_BITAR
Q8SQG8, HYAL2_BOVINA0A7T9L375, HYAL2_HEMLEQ12891, HYAL2_HUMAN
P0DRN8, HYAL2_LOXINO35632, HYAL2_MOUSEQ9Z2Q3, HYAL2_RAT
Q8SQG7, HYAL2_SHEEPA0A0C9QKT6, HYAL2_TITBAW0HFN9, HYAL2_TITSE
A3QVN4, HYAL3_CERCEO43820, HYAL3_HUMANQ8VEI3, HYAL3_MOUSE
Q6RHW2, HYAL3_PIGQ5REQ1, HYAL3_PONABQ76HM9, HYAL3_RAT
A3QVN5, HYAL4_CERCEQ2M3T9, HYAL4_HUMANQ05A56, HYAL4_MOUSE
Q812F3, HYAL5_MOUSEQ05FZ2, HYALA_VESGEP0DRN5, HYALA_VESTR
P49370, HYALA_VESVUC0HLL5, HYALB_VESVEP23613, HYALP_CAVPO
P38567, HYALP_HUMANP38568, HYALP_MACFAP48794, HYALP_MOUSE
P38566, HYALP_RABITQ62803, HYALP_RATP0DRN6, HYAL_ACANA
Q95PD7, HYAL_APICCQ08169, HYAL_APIMEA0A2H4Z8F4, HYAL_BOTAT
E2ADC1, HYAL_CAMFOI0CME8, HYAL_CONAQI0CME7, HYAL_CONCN
C0HKM3, HYAL_CONPUJ3S820, HYAL_CROADB3EWP2, HYAL_CRODU
A0A0S4JYH2, HYAL_CUPSAP49371, HYAL_DOLMAA3QVN2, HYAL_ECHOC
A3QVN6, HYAL_ECHPLR4J7Z9, HYAL_LOXINQ9XZ48, HYAL_LUTLO
A0A348G5W8, HYAL_ODOMOK4PBL9, HYAL_ORNANP86274, HYAL_PHOKE
Q9U6V9, HYAL_POLANA0ABM1IHN5, HYAL_POLDOP86687, HYAL_POLPI
K7ZPU7, HYAL_PTEABK7ZMF5, HYAL_PTEVLP0DRN4, HYAL_SCOPL
Q801Z8, HYAL_SYNHOE5RWZ0, HYAL_SYNVEE0XKJ9, HYAL_TABYA
P0DYJ2, HYAL_TITOBJ9XYC6, HYAL_TLIVAP0CH89, HYAL_VESMC
P86875, HYAL_VESMGP15316, HYLP1_BPH44Q54699, HYLP2_BPH45
P26831, NAGH_CLOPE
BRENDA3.2.1.35
MetaCyc3.2.1.35
KEGG Ligand Database for Enzyme Nomenclature3.2.1.35
MEDLINEFind literature relating to 3.2.1.35

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-