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ENZYME entry: EC 3.2.1.49

Accepted Name
Alpha-N-acetylgalactosaminidase.
Alternative Name(s)
Alpha-galactosidase B.
Alpha-GalNAcase.
Alpha-NAGA.
Reaction catalysed
Cleavage of non-reducing alpha-(1->3)-N-acetylgalactosamine residues from human blood group A and AB mucin glycoproteins, Forssman hapten and blood group A lacto series glycolipids
Comment(s)
The human lysosomal enzyme is involved in the degradation of blood type A epitope.
Cross-references
PROSITEPDOC00443
BRENDA3.2.1.49
EC2PDB3.2.1.49
ExplorEnz3.2.1.49
PRIAM enzyme-specific profiles3.2.1.49
KEGG Ligand Database for Enzyme Nomenclature3.2.1.49
IUBMB Enzyme Nomenclature3.2.1.49
IntEnz3.2.1.49
MEDLINEFind literature relating to 3.2.1.49
MetaCyc3.2.1.49
UniProtKB/Swiss-Prot
Q5LGW9, G1092_BACFN;  A4Q8F7, GH109_ELIME;  Q8ECL7, GH109_SHEON;  
A4Q8G1, GH109_TANFO;  P83127, NAGAB_BOSIN;  Q58DH9, NAGAB_BOVIN;  
Q90744, NAGAB_CHICK;  P17050, NAGAB_HUMAN;  Q9QWR8, NAGAB_MOUSE;  
Q66H12, NAGAB_RAT;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-