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ENZYME entry: EC 3.2.1.62

Accepted Name
Glycosylceramidase.
Alternative Name(s)
Phloretin-glucosidase.
Phlorizin hydrolase.
Reaction catalysed
Glycosyl-N-acylsphingosine + H(2)O <=> N-acylsphingosine + a sugar
Comment(s)
  • Broad specificity (cf. EC 3.2.1.45 and EC 3.2.1.46).
  • Also hydrolyzes phlorizin to phloretin and glucose.
  • The intestinal enzyme is a complex which also catalyzes the reaction of EC 3.2.1.108.
Cross-references
PROSITEPDOC00495
BRENDA3.2.1.62
EC2PDB3.2.1.62
ExplorEnz3.2.1.62
PRIAM enzyme-specific profiles3.2.1.62
KEGG Ligand Database for Enzyme Nomenclature3.2.1.62
IUBMB Enzyme Nomenclature3.2.1.62
IntEnz3.2.1.62
MEDLINEFind literature relating to 3.2.1.62
MetaCyc3.2.1.62
Rhea expert-curated reactions3.2.1.62
UniProtKB/Swiss-Prot
P09848, LPH_HUMAN;  P09849, LPH_RABIT;  Q02401, LPH_RAT;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
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