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ENZYME entry: EC 3.2.1.67

Accepted Name
Galacturonan 1,4-alpha-galacturonidase.
Alternative Name(s)
Exopolygalacturonase.
Galacturan 1,4-alpha-galacturonidase.
Poly(galacturonate) hydrolase.
Reaction catalysed
((1->4)-alpha-D-galacturonide)(n) + H(2)O <=> ((1->4)-alpha-D-galacturonide)(n-1) + D-galacturonate
Comment(s)
  • The enzyme hydrolyzes the first glycosidic bond from the non-reducing end of the substrate.
  • It is specific for saturated oligomers of D-homogalacturonan, and is unable to degrade unsaturated substrates or methyl-esterified substrates.
Cross-references
PROSITEPDOC00415
BRENDA3.2.1.67
EC2PDB3.2.1.67
ExplorEnz3.2.1.67
PRIAM enzyme-specific profiles3.2.1.67
KEGG Ligand Database for Enzyme Nomenclature3.2.1.67
IUBMB Enzyme Nomenclature3.2.1.67
IntEnz3.2.1.67
MEDLINEFind literature relating to 3.2.1.67
MetaCyc3.2.1.67
Rhea expert-curated reactions3.2.1.67
UniProtKB/Swiss-Prot
P39130, LPLD_BACSU;  A9KTB9, LPLD_LACP7;  D3T426, LPLD_THEIA;  
I3VRU1, LPLD_THESW;  P49062, PGLR1_ARATH;  P26216, PGLR1_MAIZE;  
P49063, PGLR2_ARATH;  P35338, PGLR2_MAIZE;  Q6H9K0, PGLR2_PLAAC;  
P35339, PGLR3_MAIZE;  B0YDE8, PGLRX_ASPFC;  B8NG16, PGLRX_ASPFN;  
Q4WCZ8, PGLRX_ASPFU;  A2R060, PGLRX_ASPNC;  Q27UB3, PGLRX_ASPNG;  
Q0CGP0, PGLRX_ASPTN;  Q00293, PGLRX_ASPTU;  Q00359, PGLRX_COCCA;  
A1DLC1, PGLRX_NEOFI;  P24548, PGLR_OENOR;  Q5ASG9, PGLX1_EMENI;  
Q5ARN5, PGLX2_EMENI;  A2QW66, PGXA_ASPNC;  Q27UB2, PGXA_ASPNG;  
B0YAA4, PGXB_ASPFC;  B8NX60, PGXB_ASPFN;  Q4WBK6, PGXB_ASPFU;  
A2QHG0, PGXB_ASPNC;  Q27UB1, PGXB_ASPNG;  Q2TW03, PGXB_ASPOR;  
Q0C7H7, PGXB_ASPTN;  Q873X6, PGXB_EMENI;  A1DAX2, PGXB_NEOFI;  
B0XYC4, PGXC_ASPFC;  B8MZZ6, PGXC_ASPFN;  Q4WX94, PGXC_ASPFU;  
A2QEW2, PGXC_ASPNC;  Q27UB0, PGXC_ASPNG;  Q2UQ40, PGXC_ASPOR;  
Q0CXI3, PGXC_ASPTN;  A1D7I1, PGXC_NEOFI;  B8NJB0, RGXA_ASPFN;  
A2QBB4, RGXA_ASPNC;  Q2EQQ2, RGXA_ASPNG;  Q2UP32, RGXA_ASPOR;  
A2RAY7, RGXC_ASPNC;  A1D415, RGXC_NEOFI;  I1BPS7, RPG13_RHIO9;  
I1BYN5, RPG14_RHIO9;  I1BYM7, RPG15_RHIO9;  I1BYN6, RPG16_RHIO9;  
W8P8Q3, SALK6_KALTU;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.1.-
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