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ENZYME entry: EC 3.2.1.68

Accepted Name
Isoamylase.
Alternative Name(s)
Debranching enzyme.
Reaction catalysed
Hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limit dextrins
Comment(s)
  • Also readily hydrolyzes amylopectin.
  • Differs from EC 3.2.1.41 and EC 3.2.1.142 by its inability to hydrolyze pullulan, and by limited action on alpha-limit dextrins.
  • Maltose is the smallest sugar it can release from an alpha-(1->6)- linkage.
Cross-references
BRENDA3.2.1.68
EC2PDB3.2.1.68
ExplorEnz3.2.1.68
PRIAM enzyme-specific profiles3.2.1.68
KEGG Ligand Database for Enzyme Nomenclature3.2.1.68
IUBMB Enzyme Nomenclature3.2.1.68
IntEnz3.2.1.68
MEDLINEFind literature relating to 3.2.1.68
MetaCyc3.2.1.68
Rhea expert-curated reactions3.2.1.68
UniProtKB/Swiss-Prot
O04196, ISOA1_ARATH;  D0TZF0, ISOA1_ORYSJ;  Q6AU80, ISOA2_ORYSJ;  
Q9M0S5, ISOA3_ARATH;  B9G434, ISOA3_ORYSJ;  O32611, ISOA_FLASP;  
P10342, ISOA_PSEAY;  P26501, ISOA_PSEUM;  

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