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ENZYME

ENZYME entry: EC 3.2.2.22

Accepted Name
rRNA N-glycosylase
Alternative Name(s)
rRNA N-glycosidase
Reaction catalysed
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA
Comment(s)
  • Ricin A-chain and related toxins show this activity.
  • Naked rRNA is attacked more slowly than rRNA in intact ribosomes.
  • Naked rRNA from Escherichia coli is cleaved at a corresponding position.
Cross-references
BRENDA3.2.2.22
EC2PDB3.2.2.22
ExplorEnz3.2.2.22
PRIAM enzyme-specific profiles3.2.2.22
KEGG Ligand Database for Enzyme Nomenclature3.2.2.22
IUBMB Enzyme Nomenclature3.2.2.22
IntEnz3.2.2.22
MEDLINEFind literature relating to 3.2.2.22
MetaCyc3.2.2.22
Rhea expert-curated reactions3.2.2.22
UniProtKB/Swiss-Prot
P11140, ABRA_ABRPRQ06077, ABRB_ABRPRP28590, ABRC_ABRPR
Q06076, ABRD_ABRPRQ9M6E9, AGGL_ABRPRP06750, AGGL_RICCO
P10593, ALB3_MAIZEP83572, ARALA_ARAELP84072, CHAR_MOMCH
Q00531, JI60_HORVUP36230, LECA_IRIHOC0HLZ4, LYOPH_LYOSH
P81446, ML1_VISALQ6H266, ML2_VISALP82683, ML3_VISAL
Q6ITZ3, ML4_VISALP33183, NIGB_SAMNIQ1JPL7, PME18_ARATH
P02879, RICI_RICCOP24476, RIP0_DIACAP33185, RIP1_BRYDI
Q9FRX4, RIP1_CUCFIQ5F0I3, RIP1_GYNPEQ7M1L6, RIP1_GYPVA
P22244, RIP1_HORVUP56568, RIP1_LUFAEP16094, RIP1_MOMCH
P10297, RIP1_PHYAMP93543, RIP1_SAMNIQ7M1L7, RIP1_SAPOC
P98185, RIP1_SAPOFP56626, RIP1_TRIANP98184, RIP2_BRYDI
P24477, RIP2_DIACAC0HM39, RIP2_GYPVAP04399, RIP2_HORVU
P29339, RIP2_MOMBAQ40772, RIP2_PHYAMP34967, RIP2_PHYDI
P27559, RIP2_SAPOFP23029, RIP2_TRIKIP25891, RIP3_MAIZE
P24817, RIP3_MOMCHP27560, RIP3_SAPOFP24475, RIP3_SURMU
Q6EH50, RIP4_PHYHEP27561, RIP4_SAPOFQ41389, RIP5_SAPOF
P20656, RIP6_SAPOFQ41391, RIP7_SAPOFP25892, RIP9_MAIZE
Q7M1Z2, RIP9_SAPOFQ00465, RIPA_LUFAEQ03464, RIPA_PHYAM
P22851, RIPB_LUFAEP86144, RIPD1_PHYDIP85208, RIPD2_PHYDI
P33186, RIPG_SURMUP16093, RIPK_TRIKIP84853, RIPL1_PHYDI
P84854, RIPL2_PHYDIP85101, RIPLY_SILCHP84073, RIPL_LUFAE
Q9M654, RIPM_POLMLP21326, RIPP_MIRJAP20655, RIPS_MOMCO
P23339, RIPS_PHYAMP24478, RIPS_TRIKIQ9M653, RIPT_POLML
P09989, RIPT_TRIKIP80750, RIPX_CUCPEP28522, RIPX_MAIZE
P84531, RIP_CUCMOP84786, RIP_DRIMAP83324, RIP_FLAVE
P83245, RIP_LENTRP84530, RIP_LUFACP83323, RIP_SIRGR
I1C083, RLT1_RHIO9Q41358, SNAIB_SAMNIO22415, SNAIF_SAMNI
Q779K4, STXA_BP788P09385, STXA_BP933P08026, STXA_BPH19
P10149, STXA_BPH30Q32GM1, STXA_SHIDSQ9FBI2, STXA_SHIDY
Q70US9, VOLK_ADEVO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-