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ENZYME entry: EC 3.2.2.25

Accepted Name
N-methyl nucleosidase.
Alternative Name(s)
7-methylxanthosine nucleosidase.
methylpurine nucleosidase.
N-MeNase.
N-methyl nucleoside hydrolase.
Reaction catalysed
7-methylxanthosine + H2O <=> 7-methylxanthine + D-ribose + H(+)
Comment(s)
  • Preferentially hydrolyzes 3- and 7-methylpurine nucleosides, such as 3-methylxanthosine, 3-methyladenosine and 7-methylguanosine.
  • Hydrolysis of 7-methylxanthosine to form 7-methylxanthine is the second step in the caffeine biosynthesis pathway.
Cross-references
BRENDA3.2.2.25
EC2PDB3.2.2.25
ExplorEnz3.2.2.25
PRIAM enzyme-specific profiles3.2.2.25
KEGG Ligand Database for Enzyme Nomenclature3.2.2.25
IUBMB Enzyme Nomenclature3.2.2.25
IntEnz3.2.2.25
MEDLINEFind literature relating to 3.2.2.25
MetaCyc3.2.2.25
Rhea expert-curated reactions3.2.2.25

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-