ID   3.2.2.6
DE   ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase.
AN   NAD(+) nucleosidase.
AN   NADase.
AN   NAD hydrolase.
AN   nicotinamide adenine dinucleotide nucleosidase.
CA   H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide.
CC   -!- This multiunctional enzyme catalyzes both the synthesis and
CC       hydrolysis of cyclic ADP-ribose, a calcium messenger that can
CC       mobilize intracellular Ca(2+) stores and activate Ca(2+) influx to
CC       regulate a wide range of physiological processes.
CC   -!- In addition, the enzyme also catalyzes EC 2.4.99.20.
CC   -!- It is also able to act on beta-nicotinamide D-ribonucleotide. cf.
CC       EC 3.2.2.5.
DR   A0A009IHW8, ABTIR_ACIB9;  Q9C7X0, ADR2_ARATH ;  G8SD34, APTIR_ACTS5;
DR   I1GTC2, BDTIR_BRADI;  Q10588, BST1_HUMAN ;  Q64277, BST1_MOUSE ;
DR   Q63072, BST1_RAT   ;  P28907, CD38_HUMAN ;  Q5VAN0, CD38_MACFA ;
DR   P56528, CD38_MOUSE ;  Q9MZ03, CD38_RABIT ;  Q64244, CD38_RAT   ;
DR   Q9LUJ8, CHL1_ARATH ;  F4I902, CHS1_ARATH ;  F4KIF3, CSA1_ARATH ;
DR   Q9SZ66, DSC1_ARATH ;  F4JWM0, DSC2_ARATH ;  O95256, I18RA_HUMAN;
DR   Q9Z2B1, I18RA_MOUSE;  Q13478, IL18R_HUMAN;  Q61098, IL18R_MOUSE;
DR   Q9NPH3, IL1AP_HUMAN;  P59822, IL1AP_MACMU;  Q61730, IL1AP_MOUSE;
DR   Q63621, IL1AP_RAT  ;  P14778, IL1R1_HUMAN;  P13504, IL1R1_MOUSE;
DR   Q02955, IL1R1_RAT  ;  Q01638, ILRL1_HUMAN;  P14719, ILRL1_MOUSE;
DR   Q62611, ILRL1_RAT  ;  Q9HB29, ILRL2_HUMAN;  Q9ERS7, ILRL2_MOUSE;
DR   Q62929, ILRL2_RAT  ;  B6ZK76, IRL1A_DANRE;  B6ZK77, IRL1B_DANRE;
DR   Q9NZN1, IRPL1_HUMAN;  P59823, IRPL1_MOUSE;  P60029, IRPL1_PANTR;
DR   Q7YQL9, IRPL1_PONPY;  P59824, IRPL1_RAT  ;  Q9NP60, IRPL2_HUMAN;
DR   Q9ERS6, IRPL2_MOUSE;  Q40253, L6_LINUS   ;  O48573, LAZ5_ARATH ;
DR   Q27312, NADA_APLKU ;  Q9C5Q9, P2A05_ARATH;  Q9FHE8, P2A06_ARATH;
DR   Q9FHE9, P2A08_ARATH;  A1AY86, PDTIR_PARDP;  F4HT77, RBA1_ARATH ;
DR   F4I594, RLM1A_ARATH;  Q9CAK1, RLM1B_ARATH;  Q9FT77, RLM3_ARATH ;
DR   A0A290U7C4, ROQ1_NICBE ;  F4J339, RPP1_ARATH ;  F4JT78, RPP2A_ARATH;
DR   F4JT80, RPP2B_ARATH;  F4JT82, RPP2C_ARATH;  O49471, RPP2D_ARATH;
DR   F4JNA9, RPP4_ARATH ;  F4JNB7, RPP5_ARATH ;  Q9FHF0, RPS4B_ARATH;
DR   Q9SCX6, RPS4L_ARATH;  Q9SCX7, RPS4R_ARATH;  C4B7M7, RPS4W_ARATH;
DR   Q9XGM3, RPS4_ARATH ;  F4KHH8, RPS6C_ARATH;  P0DKH6, RPS6R_ARATH;
DR   V9M2S5, RPV1_VITRO ;  V9M398, RUN1_VITRO ;  Q86DA5, SARM1_CAEEL;
DR   F1QWA8, SARM1_DANRE;  Q6IDD9, SARM1_DROME;  Q6SZW1, SARM1_HUMAN;
DR   Q6PDS3, SARM1_MOUSE;  I3L5V6, SARM1_PIG  ;  D3ZUM2, SARM1_RAT  ;
DR   O23530, SNC1_ARATH ;  P0DUE1, STING_CRAGI;  Q9FI14, TAO1_ARATH ;
DR   A0A151EH88, TCPA_THEAD ;  Q2YPC4, TCPB_BRUA2 ;  C0RGW8, TCPB_BRUMB ;
DR   Q8YF53, TCPB_BRUME ;  A0A0H2V8B5, TCPC_ECOL6 ;  Q833J1, TCPF_ENTFA ;
DR   A0A1I4KS07, TCPO_METOL ;  Q0WSX8, TIK_ARATH  ;  Q54HT1, TIRA_DICDI ;
DR   P0DTS9, TIRS_STAAS ;  Q40392, TMVRN_NICGU;  Q9SYC9, VAP14_ARATH;
DR   F4KHI3, VICTR_ARATH;  O82500, Y4117_ARATH;  P96648, YDDK_BACSU ;
//