ID 3.3.2.7 DE hepoxilin-epoxide hydrolase. AN hepoxilin A3 hydrolase. AN hepoxilin epoxide hydrolase. AN hepoxylin hydrolase. CA (5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + CA H2O = (5Z,9E,14Z)-(8xi,11xi,12S)-8,11,12-trihydroxyicosa-5,9,14- CA trienoate. CC -!- Converts hepoxilin A3 into trioxilin A3. CC -!- Highly specific for the substrate, having only slight activity with CC other epoxides such as leukotriene A4 and styrene oxide. CC -!- Probably plays a modulatory role in inflammation, vascular CC physiology, systemic glucose metabolism and neurological function. //