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ENZYME entry: EC 3.4.11.14

Accepted Name
Cytosol alanyl aminopeptidase.
Alternative Name(s)
Aminopolypeptidase.
Arylamidase.
Cytosol aminopeptidase III.
Liver aminopeptidase.
Puromycin-sensitive aminopeptidase.
Soluble alanyl aminopeptidase.
Reaction catalysed
Release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides
Cofactor(s)
Cobalt cation or Zn(2+).
Comment(s)
  • A puromycin-sensitive, cobalt-activated zinc-sialoglycoprotein that is generally cytosolic.
  • Multiple forms are widely distributed in mammalian tissues and body fluids.
Cross-references
BRENDA3.4.11.14
EC2PDB3.4.11.14
ExplorEnz3.4.11.14
PRIAM enzyme-specific profiles3.4.11.14
KEGG Ligand Database for Enzyme Nomenclature3.4.11.14
IUBMB Enzyme Nomenclature3.4.11.14
IntEnz3.4.11.14
MEDLINEFind literature relating to 3.4.11.14
MetaCyc3.4.11.14
Rhea expert-curated reactions3.4.11.14
UniProtKB/Swiss-Prot
Q8H0S9, PSA_ARATH;  Q4TT88, PSA_CAEEL;  P55786, PSA_HUMAN;  
Q11011, PSA_MOUSE;  B7EA73, PSA_ORYSJ;  

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