A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.4.11.2
| Accepted Name |
|---|
| Membrane alanyl aminopeptidase.
|
| Alternative Name(s) |
|---|
| Amino-oligopeptidase. |
| Aminopeptidase M. |
| Aminopeptidase N. |
| Membrane alanine aminopeptidase. |
| Membrane aminopeptidase I. |
| Microsomal aminopeptidase. |
| Particle-bound aminopeptidase. |
| Peptidase E. |
| Reaction catalysed |
|---|
| Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide |
| Cofactor(s) |
|---|
| Zn(2+).
|
| Comment(s) |
|---|
|
| Cross-references |
|---|
| PROSITE | PDOC00129 |
| BRENDA | 3.4.11.2 |
| EC2PDB | 3.4.11.2 |
| ExplorEnz | 3.4.11.2 |
| PRIAM enzyme-specific profiles | 3.4.11.2 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.11.2 |
| IUBMB Enzyme Nomenclature | 3.4.11.2 |
| IntEnz | 3.4.11.2 |
| MEDLINE | Find literature relating to 3.4.11.2 |
| MetaCyc | 3.4.11.2 |
| UniProtKB/Swiss-Prot |
| Q10736, AMPN_ACEPA; | P79098, AMPN_BOVIN; | P79143, AMPN_CANLF; |
| P37893, AMPN_CAUVC; | P04825, AMPN_ECOLI; | P79171, AMPN_FELCA; |
| Q10737, AMPN_HAECO; | P45274, AMPN_HAEIN; | P81731, AMPN_HELAM; |
| P15144, AMPN_HUMAN; | P37896, AMPN_LACDL; | Q10730, AMPN_LACHE; |
| Q9CIQ1, AMPN_LACLA; | P0C2T8, AMPN_LACLC; | Q48656, AMPN_LACLL; |
| A2RI32, AMPN_LACLM; | P91885, AMPN_MANSE; | P97449, AMPN_MOUSE; |
| P15145, AMPN_PIG; | P91887, AMPN_PLUXY; | P15541, AMPN_RABIT; |
| P15684, AMPN_RAT; | Q11010, AMPN_STRLI; | Q6Z6L4, APM1A_ORYSJ; |
| Q0J5V5, APM1B_ORYSJ; | Q0J2B5, APM1C_ORYSJ; | Q6K4E7, APM1D_ORYSJ; |
| Q8VZH2, APM1_ARATH; |
|
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