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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 3.4.11.4

Accepted Name
Tripeptide aminopeptidase.
Alternative Name(s)
Aminoexotripeptidase.
Aminotripeptidase.
Imidoendopeptidase.
Lymphopeptidase.
Peptidase B.
Tripeptidase.
Reaction catalysed
Release of the N-terminal residue from a tripeptide
Cofactor(s)
Zn(2+).
Comment(s)
  • Widely distributed in mammalian tissues.
  • Belongs to peptidase family M9.
  • Formerly EC 3.4.1.3.
Cross-references
BRENDA3.4.11.4
EC2PDB3.4.11.4
ExplorEnz3.4.11.4
PRIAM enzyme-specific profiles3.4.11.4
KEGG Ligand Database for Enzyme Nomenclature3.4.11.4
IUBMB Enzyme Nomenclature3.4.11.4
IntEnz3.4.11.4
MEDLINEFind literature relating to 3.4.11.4
MetaCyc3.4.11.4
UniProtKB/Swiss-Prot
Q76HM7, PEPT2_LACLC;  A0KIP7, PEPT_AERHH;  A4SPD7, PEPT_AERS4;  
Q5E0X3, PEPT_ALIF1;  B6ER23, PEPT_ALISL;  A8ML45, PEPT_ALKOO;  
C3P5E3, PEPT_BACAA;  C3L855, PEPT_BACAC;  A0RHB6, PEPT_BACAH;  
Q81WU4, PEPT_BACAN;  B7JJ20, PEPT_BACC0;  Q732Y5, PEPT_BACC1;  
B7ITJ6, PEPT_BACC2;  C1ENW4, PEPT_BACC3;  B7HDL9, PEPT_BACC4;  
B7HKU6, PEPT_BACC7;  A7GR91, PEPT_BACCN;  B9IV41, PEPT_BACCQ;  
Q81A48, PEPT_BACCR;  Q636T5, PEPT_BACCZ;  Q5LFT7, PEPT_BACFN;  
Q64WS4, PEPT_BACFR;  Q6HF68, PEPT_BACHK;  Q65D74, PEPT_BACLD;  
A8FIY2, PEPT_BACP2;  Q5WK52, PEPT_BACSK;  P55179, PEPT_BACSU;  
Q89YZ7, PEPT_BACTN;  A7ZAB2, PEPT_BACVZ;  A9VR36, PEPT_BACWK;  
C0ZDI3, PEPT_BREBN;  Q8R922, PEPT_CALS4;  A8AHU0, PEPT_CITK8;  
Q97LS8, PEPT_CLOAB;  A7FPG2, PEPT_CLOB1;  C3L049, PEPT_CLOB6;  
A5HYY2, PEPT_CLOBH;  C1FSB0, PEPT_CLOBJ;  B1IEF5, PEPT_CLOBK;  
A7GAK0, PEPT_CLOBL;  B1KV00, PEPT_CLOBM;  A0Q3I1, PEPT_CLONN;  
Q0TV42, PEPT_CLOP1;  Q8XPD8, PEPT_CLOPE;  Q0SWT9, PEPT_CLOPS;  
B8G1J0, PEPT_DESHD;  Q24VU3, PEPT_DESHY;  A7ZKR7, PEPT_ECO24;  
B7UQ36, PEPT_ECO27;  B7MJB5, PEPT_ECO45;  P65804, PEPT_ECO57;  
B7MTQ8, PEPT_ECO81;  C4ZS67, PEPT_ECOBW;  B1XA37, PEPT_ECODH;  
A7ZZ82, PEPT_ECOHS;  A1AA21, PEPT_ECOK1;  Q0TIU6, PEPT_ECOL5;  
P65803, PEPT_ECOL6;  B1IUE0, PEPT_ECOLC;  P29745, PEPT_ECOLI;  
B7N3N7, PEPT_ECOLU;  B6I9K6, PEPT_ECOSE;  Q1RD26, PEPT_ECOUT;  
C5BFN3, PEPT_EDWI9;  Q835J5, PEPT_ENTFA;  B7LQ18, PEPT_ESCF3;  
B1YFS8, PEPT_EXIS2;  C4L0I9, PEPT_EXISA;  P58794, PEPT_FUSNN;  
P81207, PEPT_FUSNP;  Q5KZ39, PEPT_GEOKA;  C5DAS5, PEPT_GEOSW;  
A4INW9, PEPT_GEOTN;  Q4QK58, PEPT_HAEI8;  A5UBV7, PEPT_HAEIE;  
A5UEI5, PEPT_HAEIG;  P45172, PEPT_HAEIN;  B8CWQ0, PEPT_HALOH;  
B5XSP2, PEPT_KLEP3;  B2GC19, PEPT_LACF3;  Q9L4G1, PEPT_LACHE;  
Q9CEM7, PEPT_LACLA;  P0C2T7, PEPT_LACLC;  Q84BV2, PEPT_LACLH;  
Q76HM5, PEPT_LACLL;  A2RMN0, PEPT_LACLM;  Q02X44, PEPT_LACLS;  
A9KT72, PEPT_LACP7;  Q1WTV4, PEPT_LACS1;  Q38X92, PEPT_LACSS;  
Q92AM8, PEPT_LISIN;  C1KW79, PEPT_LISMC;  Q71YN8, PEPT_LISMF;  
B8DDX7, PEPT_LISMH;  Q8Y6B1, PEPT_LISMO;  A0AJN4, PEPT_LISW6;  
B1HZ48, PEPT_LYSSC;  B9EAD7, PEPT_MACCJ;  Q8CXN0, PEPT_OCEIH;  
A6L8T2, PEPT_PARD8;  Q9CP05, PEPT_PASMU;  Q6D4E3, PEPT_PECAS;  
C6DFW1, PEPT_PECCP;  Q6LR24, PEPT_PHOPR;  B5F8C6, PEPT_SALA4;  
A9MG86, PEPT_SALAR;  Q57QC7, PEPT_SALCH;  B5FK77, PEPT_SALDC;  
B5QXA9, PEPT_SALEP;  B5RB75, PEPT_SALG2;  B4TFK5, PEPT_SALHS;  
B4T3R6, PEPT_SALNS;  Q5PMK2, PEPT_SALPA;  C0Q764, PEPT_SALPC;  
B5BAE8, PEPT_SALPK;  B4TTK0, PEPT_SALSV;  Q8Z7H6, PEPT_SALTI;  
P26311, PEPT_SALTY;  A8GDC2, PEPT_SERP5;  B0TPD4, PEPT_SHEHH;  
A8H6S3, PEPT_SHEPA;  A8G0I7, PEPT_SHESH;  B1KHS7, PEPT_SHEWM;  
B2TZ80, PEPT_SHIB3;  Q31ZK3, PEPT_SHIBS;  Q32EY5, PEPT_SHIDS;  
Q0T5R1, PEPT_SHIF8;  Q83RR6, PEPT_SHIFL;  Q3Z2Z2, PEPT_SHISS;  
A7WZN6, PEPT_STAA1;  A6TZM2, PEPT_STAA2;  Q2FIP8, PEPT_STAA3;  
Q2G064, PEPT_STAA8;  A5IQU7, PEPT_STAA9;  Q2YSI6, PEPT_STAAB;  
Q5HHS7, PEPT_STAAC;  A6QF52, PEPT_STAAE;  P65805, PEPT_STAAM;  
P65806, PEPT_STAAN;  Q6GIP8, PEPT_STAAR;  Q6GB87, PEPT_STAAS;  
A8Z018, PEPT_STAAT;  Q8NXM6, PEPT_STAAW;  B9DK09, PEPT_STACT;  
Q5HQY6, PEPT_STAEQ;  Q8CPZ6, PEPT_STAES;  Q4L4G8, PEPT_STAHJ;  
Q49VU2, PEPT_STAS1;  Q3K0C3, PEPT_STRA1;  Q8E4E2, PEPT_STRA3;  
Q8DYT4, PEPT_STRA5;  C0M8H1, PEPT_STRE4;  A8AXT3, PEPT_STRGC;  
Q8CWX9, PEPT_STRMU;  Q9A0F4, PEPT_STRP1;  Q04KS5, PEPT_STRP2;  
P0DD00, PEPT_STRP3;  Q5XCU7, PEPT_STRP6;  C1C6Y4, PEPT_STRP7;  
Q8P1H9, PEPT_STRP8;  Q1JCH7, PEPT_STRPB;  Q1JMF5, PEPT_STRPC;  
Q1JHK2, PEPT_STRPD;  Q1J7C3, PEPT_STRPF;  A2RF89, PEPT_STRPG;  
B1IBG7, PEPT_STRPI;  B8ZPG1, PEPT_STRPJ;  Q48U99, PEPT_STRPM;  
Q97R31, PEPT_STRPN;  P0DD01, PEPT_STRPQ;  B2IPG2, PEPT_STRPS;  
B5XKT3, PEPT_STRPZ;  Q8DQ05, PEPT_STRR6;  A4W1Q9, PEPT_STRS2;  
C0MGM6, PEPT_STRS7;  A3CNH0, PEPT_STRSV;  A4VVF5, PEPT_STRSY;  
Q5LZL2, PEPT_STRT1;  Q5M465, PEPT_STRT2;  Q03KI4, PEPT_STRTD;  
B9DU35, PEPT_STRU0;  C1CE02, PEPT_STRZJ;  C1CK88, PEPT_STRZP;  
C1CRC4, PEPT_STRZT;  A5EYJ8, PEPT_VIBC3;  Q9KMY6, PEPT_VIBCH;  
C3LUK2, PEPT_VIBCM;  Q87GX2, PEPT_VIBPA;  B7VSC8, PEPT_VIBTL;  
Q7MDF5, PEPT_VIBVY;  A7FH54, PEPT_YERP3;  Q1C6R3, PEPT_YERPA;  
B2K719, PEPT_YERPB;  Q8ZFR0, PEPT_YERPE;  A9R0M2, PEPT_YERPG;  
Q1CI51, PEPT_YERPN;  A4TLP0, PEPT_YERPP;  Q669P7, PEPT_YERPS;  
B1JI59, PEPT_YERPY;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-